[1]袁正,肖湘生,刘士远,等.磁共振扩散加权成像在肝癌TACE术后随访中的定性和定量应用[J].介入放射学杂志,2007,(12):820.
　YUAN Zheng,XIAO Xiang-sheng,LIU Shi-yuan,et al.Diffusion-weighted MR imaging for liver cancer follow-up after transcatheter arterial chemoembolization[J].journal interventional radiology,2007,(12):820.
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磁共振扩散加权成像在肝癌TACE术后随访中的定性和定量应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年12期
页码:
820
栏目:
肿瘤介入
出版日期:
2007-12-15

文章信息/Info

Title:
Diffusion-weighted MR imaging for liver cancer follow-up after transcatheter arterial chemoembolization
作者:
袁正; 肖湘生; 刘士远; 等
２００００３上海第二军医大学长征医院影像科
Author(s):
YUAN Zheng; XIAO Xiang-sheng; LIU Shi-yuan; DONG Sheng; DONG Wei-hua; JIA Ning-yang; SUN Zhi-chao; YE Xiao-dan; YAN Bing．
Department of Radiology，Changzheng Hospital，Second Military Medical University，Shanghai２００００３，China
关键词:
磁共振成像; 扩散; 肝肿瘤; 化疗栓塞术; 随访
分类号:
R７３５.７
文献标志码:
A
摘要:
目的探讨MR扩散加权成像（DWI）在肝癌经导管动脉化疗栓塞术（TACE）后随访中定性和定量评价残留或复发肿瘤组织的能力。方法对１６例行TACE术后肝癌患者分别进行DWI、上腹部增强CT和DSA造影检查。DWI检查取扩散敏感梯度因子（b值为０及５００s／mm ２ ），利用固定参数组合的自旋回波－平面回波（SE-EPI）序列。与上腹部增强CT和DSA造影检查相对照，观察碘化油沉积灶、肿瘤坏死组织和肿瘤组织在DWI上的信号特征；分别测量TACE术后病灶的ADC值和对应的CT最大强化值，并作相关性分析。结果DWI显示TACE术后病灶内部信号较复杂，２例（２／１６）病灶碘油沉积完整，DSA检查无肿瘤染色，CT图像显示为完整的碘化油沉积灶，DWI为均匀低信号；２例（２／１６）病灶为碘油沉积但出现局部缺损，DSA检查可见缺损区肿瘤染色，DWI图像上碘油沉积区表现为低信号，肿瘤染色区为高信号；１２例（１２／１６）病灶DSA检查可见无或稍许碘油沉积，造影见大量肿瘤染色，其内可见无或轻微染色的缺血、坏死肿瘤组织，DWI图像上肿瘤染色区域表现为高信号，缺血坏死区为低或较低信号；对１４例（１４／１６）病灶内肿瘤组织的ADC值与其最大CT强化值进行相关性分析，两者存在相关性（r＝－０．７６４９０，P＜０．０１）。结论DWI是一种灵敏的检测肝癌TACE术后肝内新发病灶的无创性成像方法，可监测TACE术后病灶残留或复发活组织和坏死情况，小b值（５００s／mm ２ ）的ADC值可在一定程度上反映肿瘤的血供，可以用于肝癌TACE术后随访。

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备注/Memo

备注/Memo:
收稿日期：２００７-０７-２５
更新日期/Last Update: 2007-12-15