[1]曹晶茗,肖践明,刘中梅,等.应用冠脉血管内超声评价药物涂层支架置放后再狭窄及血管内膜增生[J].介入放射学杂志,2007,(10):657.
　CAO Jing-ming,XIAO Jian-ming,LIU Zhong-mei,et al.Evaluation of the coronary in-stent restenosis and neointimal hyperplasia between two kinds of drug eluting stent implantation under intravenous ultrasound[J].journal interventional radiology,2007,(10):657.
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应用冠脉血管内超声评价药物涂层支架置放后再狭窄及血管内膜增生()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年10期
页码:
657
栏目:
心脏介入
出版日期:
2007-10-15

文章信息/Info

Title:
Evaluation of the coronary in-stent restenosis and neointimal hyperplasia between two kinds of drug eluting stent implantation under intravenous ultrasound
作者:
曹晶茗; 肖践明; 刘中梅; 等
６５００３２昆明医学院第一附属医院心内科
Author(s):
CAO Jing-ming; XIAO Jian-ming; LIU Zhong-mei; LIU Rong; CAI Hong-yan; ZHANG Yun-hong; XU Fong; GUO Tao; HAN Ming-hua．
Department of Cardiology，First Affiliated Hospital，Kunming Medical College，Kunming６４００３１，China
关键词:
冠状动脉疾病; 支架; 再狭窄; 冠脉内超声
分类号:
R７１４.２２
文献标志码:
A
摘要:
目的应用冠脉内超声测量支架置入６个月后内膜增生厚度，准确比较不同支架再狭窄率。方法选择５７例药物洗脱支架（DES）置入术后４～８（６±２）个月同意复查冠脉造影及冠脉血管内超声的冠心病（CHD）住院患者，分为Cypher支架组（２５例）和Firebird支架组（３２例），及同期４９１例植入金属裸支架（BMS）CHD患者，测量支架置入后６个月时的内膜增生并进行比较。结果冠脉造影显示DES发生再狭窄Cypher组１１例，Firebird组１０例，裸支架组２５例。再狭窄率分别为８．４％，８．９％和１０．０％。DES两组差异无统计学意义，裸支架组与Cypher组及Firebird组相比较差异有显著性。冠脉内超声检查结果显示DES组中Cypher支架新生内膜面积为（１．１１±０．８９）mm ２ ，支架再狭窄率（９．０±０．１）％；Firebird组为（１．１３±０．０８）mm ２ ，支架再狭窄率（１０．０±０．２）％。DES两组间比较差异无统计学意义。裸支架组支架新生内膜面积为（１．４４±０．０４）mm ２ ，再狭窄率为（２１．０±０．１）％，与DES两组比较，有显著的统计学差异（P＜０．０５）。支架两端的节段狭窄率DES组中近端的节段狭窄Cypher组（０．４３±０．２５）％与Firebird组（０．４０±０．１５）％都显著高于裸金属支架组（０．２９±０．１３）％（P＜０．０５）。远端的节段狭窄率，三组比较差异无统计学意义。结论应用冠脉内超声评价支架内再狭窄准确度优于冠脉造影。DES降低支架内再狭窄率明显优于裸金属支架，防止支架节段狭窄，裸金属支架可能有优势。

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备注/Memo

备注/Memo:
收稿日期：２００７-０３-２０
基金项目：云南省科技厅自然科技资助合同项目
更新日期/Last Update: 2007-10-15