[1]龚少娟,邢冬娟,徐爱民,等.经皮经肝钢圈选择性门静脉栓塞术在肝门部胆管癌术前的应用[J].介入放射学杂志,2011,(07):534.
 GONG Shao-juan,XING Dong-juan,XU Ai-min,et al.Percutaneous transhepatic selective embolization of portal vein with steel coils: its preoperative application for hilar cholangiocarcinoma[J].journal interventional radiology,2011,(07):534.
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经皮经肝钢圈选择性门静脉栓塞术在肝门部胆管癌术前的应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2011年07期
页码:
534
栏目:
肿瘤介入
出版日期:
2011-07-30

文章信息/Info

Title:
Percutaneous transhepatic selective embolization of portal vein with steel coils: its preoperative application for hilar cholangiocarcinoma
作者:
龚少娟 邢冬娟 徐爱民 宋卫华 易 滨 李晓伟 朱俊军 潘春华 王 磊 张 健 姜小清 吴孟超
200438 上海 第二军医大学东方肝胆外科医院放射介入三科,胆道一科
Author(s):
GONG Shao-juan XING Dong-juan XU Ai-min SONG Wei-hua YI Bin LI Xiao-wei ZHU Jun-jun PAN Chun-hua WANG Lei ZHANG Jian JIANG Xiao-qing WU Meng-chao.
Department of Interventional Radiology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China
关键词:
肝门部胆管癌 治疗 门静脉 栓塞 肝再生
分类号:
R735.7
文献标志码:
A
摘要:
目的   探讨肝门部胆管癌扩大肝切除术前使用经皮经肝钢圈选择性门静脉栓塞术(PVE)的应用和疗效。方法   2007年4月至2009年1月收治肝门部胆管癌28例,分为两组,将预保留肝占全肝体积 < 50%、接受PVE者设为PVE组12例,其中10例最终接受联合扩大肝切除者设为PVE肝切除组;同期未行PVE而接受扩大肝切除术者为非PVE切除术组(16例)。PVE均为伴有梗阻性黄疸的Ⅵ型肝门部胆管癌,11例PVE前行预保留肝选择性胆管引流,PVE前血清胆红素(TB)为(98.0 ± 60.8)(12.4 ~ 167.9) μmol/L。PVE采用经皮经肝、同侧或对侧门静脉穿刺,放置多枚弹簧圈栓塞门静脉分支。记录PVE前后肝脏血流动力学、体积、功能等方面的变化,比较PVE肝切除组与非PVE肝切除组的术后病死率和并发症发生率。结果 12例PVE均获得成功,10例PVE后顺利施行扩大肝切除术,1例(1/12)因发现远处转移未行手术,另1例(1/12)因PVE后预保留肝叶增生不全未行手术。栓塞术后2周预保留肝叶体积增大差别有统计学意义(P < 0.05),未出现严重门静脉高压、肝功能损害等严重并发症。结论 PVE在肝门部胆管癌扩大肝切除术前的临床应用可行、有效和安全,能有效的诱导未栓塞肝叶的增生肥大,提高肿瘤的切除率,增加手术切除的安全性。

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备注/Memo

备注/Memo:
收稿日期:20101122
更新日期/Last Update: 2011-07-30