[1]李海伟,徐克,杨柯,等.可降解AZ31镁合金支架在兔腹主动脉的降解性能研究[J].介入放射学杂志,2010,(04):315.
 LI Haiwei,XU Ke,YANG Ke,et al.The degradation performance of AZ31bioabsorbable magnesium alloy stent implanted in the abdominal aorta of rabbits[J].journal interventional radiology,2010,(04):315.
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可降解AZ31镁合金支架在兔腹主动脉的降解性能研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年04期
页码:
315
栏目:
实验研究
出版日期:
2010-04-15

文章信息/Info

Title:
The degradation performance of AZ31bioabsorbable magnesium alloy stent implanted in the abdominal aorta of rabbits
作者:
李海伟徐克杨柯
110001沈阳中国医科大学附属第一医院介入放射科(李海伟、徐克、刘静、夏永辉、韩洪波、洪铎);中国科学院金属研究所(杨柯、张炳春、郑丰、谭丽丽、颜廷亭)
Author(s):
LI Hai-weiXU Ke YANG Ke LIU JingZHANG Bin-chunXIA Yong-hui ZHENG FengHAN Hong-boTAN Li-liHONG DuoYAN Ting-ting.
First Affiliated Hospital of China Medical University,Shenyang110001,China
关键词:
可降解镁合金支架兔腹主动脉降解
分类号:
R454.4
摘要:
目的初步评价可降解AZ31镁合金支架在兔主动脉的降解性能。方法将12枚可降解AZ31镁合金支架置入12只新西兰大白兔腹主动脉中。分别于术后1个月(n=3)、2个月(n=3)、3个月(n=3)及4个月(n=3)处死动物。对支架段血管进行X线照相及病理检查。结果12只实验兔在随访期存活良好。X线照相及病理显示1个月时支架形态完整,扩张完全;2个月时支架部分支杆降解断裂,失去支撑作用;3个月时大部分支架支杆降解,4个月时所有支架完全降解。支架在兔主动脉中完全降解所需时间为104.5d。结论可降解AZ31镁合金支架在兔主动脉中2个月内失去支撑作用,延长支撑时间是未来的研究方向

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2009-11-25
基金项目:高等学校博士点基金(NO.20070159011)
更新日期/Last Update: 2010-04-15