[1]宫卫东,薛克,褚延魁,等.胃冠状静脉栓塞联合部分脾栓塞治疗食管静脉曲张出血和脾功能亢进症:与外科手术比较[J].介入放射学杂志,2010,(02):105.
 GONG Weidong,XUE Ke,CHU Yankui,et al.Percutaneous transhepatic embolization of gastroesophageal varices combined with partial splenic embolization for variceal bleeding and hypersplenism:a comparison with surgery[J].journal interventional radiology,2010,(02):105.
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胃冠状静脉栓塞联合部分脾栓塞治疗食管静脉曲张出血和脾功能亢进症:与外科手术比较()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2010年02期
页码:
105
栏目:
血管介入
出版日期:
2010-02-15

文章信息/Info

Title:
Percutaneous transhepatic embolization of gastroesophageal varices combined with partial splenic embolization for variceal bleeding and hypersplenism:a comparison with surgery
作者:
宫卫东薛克褚延魁
710038西安第四军医大学唐都医院介入放射科(宫卫东、阳威、王执民、吴智群);普外科(褚延魁、王青);第四军医大学统计学教研室(杨鹏);宝鸡中心医院介入放射科(薛克、权辉)
Author(s):
GONG Wei-dongXUE Ke CHU Yan-kui WANG QingYANG WeiQUAN Hui YANG PengWANG Zhi-minWU Zhi-qun.
Tangdu Hospital,the Fourth Military Medical University,Xi'an710038,China
关键词:
食管静脉曲张脾功能亢进PGEVPSE肝硬化
分类号:
R575.2
文献标志码:
A
摘要:
目的评价经皮经肝胃冠状静脉栓塞(PEGV)联合部分脾栓塞(PSE)双介入治疗中、晚期肝硬化食管静脉曲张及门脉高压的效果。方法50例肝硬化患者,随机分为双介入组和外科手术组,分别行PEGV联合PSE治疗和断流术。随访24个月,行胃镜、腹部超声、肝功能和凝血系列检查,并统计分析结果。结果入组50例患者均顺利进行相应治疗。在双介入组,术前白细胞、血小板计数分别是(2.33±0.65)×10 9 /L和(3.63±1.05)×10 9 /L,术后24个月分别是(7.98±3.0)×10 9 /L和(163±91)×10 9 /L(P<0.05);术前门静脉直径(1.47±0.25)cm,术后24个月为(1.31±0.23)cm(P<0.05);术后24个月11例患者食管静脉曲张程度自Ⅲ级降至Ⅱ级,6例患者自Ⅱ级降至Ⅰ级。1例患者出现门脉血栓。术后24个月再出血率为16%(4/25),3例患者因再出血死亡,1例患者死于肝功能衰竭。在外科治疗组,术前白细胞和血小板计数分别是(2.2±0.60)×10 9 /L和(41.0±12.5)×10 9 /L,术后24个月分别为(9.3±2.56)×10 9 /L和(321±12.5)×10 9 /L(P<0.05);术前门静脉直径(1.43±0.22)cm,术后24个月(1.28±0.18)cm(P<0.05);术后24个月13例患者食管静脉曲张程度自Ⅲ级降至Ⅱ级,7例患者自Ⅱ级降至Ⅰ级。4例患者术后出现门脉血栓。术后24个月再出血率为20%(5/25),2例患者因再出血死亡,2例患者死于术后肝功能衰竭。结论PGEV+PSE双介入治疗在控制再出血以及提高血细胞数量方面显示出较大优势。

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备注/Memo

备注/Memo:
收稿日期:2009-00-00
更新日期/Last Update: 2010-02-15