[1]贡桔 王忠敏 陈克敏 黄钢 郑云峰 张丽云.CT引导下经皮穿刺~(125)I粒子植入治疗肺癌的临床应用[J].介入放射学杂志,2009,(09):677.
　GONG Ju WANG Zhong-min CHEN Ke-min HUANG Gang ZHENG Yun-feng ZHANG Li-yun.Clinical efficacy of CT-guided ~(125)I seed implantation therapy for advanced lung cancer[J].journal interventional radiology,2009,(09):677.
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CT引导下经皮穿刺~(125)I粒子植入治疗肺癌的临床应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2009年09期
页码:
677
栏目:
非血管介入
出版日期:
2009-09-15

文章信息/Info

Title:
Clinical efficacy of CT-guided ~(125)I seed implantation therapy for advanced lung cancer
作者:
贡桔 王忠敏 陈克敏 黄钢 郑云峰 张丽云
贡桔,王忠敏,郑云峰,张丽云,GONG Ju,WANG Zhong-min,ZHENG Yun-feng,ZHANG Li-yun(上海交通大学医学院附属瑞金医院卢湾分院,200020) 陈克敏,CHEN Ke-min(上海交通大学医学院附属瑞金医院) 黄钢,HUANG Gang(上海交通大学医学院)
Author(s):
GONG Ju WANG Zhong-min CHEN Ke-min HUANG Gang ZHENG Yun-feng ZHANG Li-yun
关键词:
肺癌 碘放射性同位素 CT引导 介入治疗 lung cancer iodine isotope CT-guidance interventional treatment
分类号:
R730.55
摘要:
目的 探讨CT引导下经皮穿刺~(125)I粒子植入治疗肺癌临床应用的安全性及疗效.方法 回顾性分析30例经肺穿刺活检、组织学或细胞学检查确诊的肺癌,其中鳞癌13例,腺癌8例,转移性肺癌9例.采用治疗计划系统(TPS)重建肺癌的三维图像,计算出~(125)I粒子植入的数量和剂量分布率,肿瘤匹配周边剂量为80～130 Gy.中位植入粒子35颗(8～83颗).结果 30例患者术后1、3、6、12个月随访,中位生存时间12个月(7～18个月),6、9、12个月累计生存率分别为100%、80.0%、23.3%,随访至12个月肿瘤完全缓解(CR)9例,部分缓解(PR)14例,无变化(NC)4例,进展(PD)3例,1、3、6、12个月总有效率(CR+PR)分别为83%、80%、80%、77%.术后随访发生气胸3例,咯血痰7例.结论 CT引导下经皮穿刺~(125)I粒子植入治疗肺癌是一种相对安全、有效、微创的方法.

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更新日期/Last Update: 2009-09-15