[1]王泷爽,纪东华.慢性肢体威胁性缺血动物模型研究进展[J].介入放射学杂志,2025,34(03):234-237.
WANG Longshuang,JI Donghua..Research progress in the establishment of animal models with chronic limb-threatening ischemia[J].journal interventional radiology,2025,34(03):234-237.
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慢性肢体威胁性缺血动物模型研究进展(
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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34
- 期数:
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2025年03
- 页码:
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234-237
- 栏目:
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专论
- 出版日期:
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2025-03-25
文章信息/Info
- Title:
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Research progress in the establishment of animal models with chronic limb-threatening ischemia
- 作者:
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王泷爽; 纪东华
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- Author(s):
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WANG Longshuang; JI Donghua.
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Department of Interventional Therapy,First Affiliated Hospital of Dalian Medical University,Dalian,Liaoning Province 116011,China
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- 关键词:
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【关键词】下肢动脉; 慢性肢体威胁性缺血; 动物模型
- 文献标志码:
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A
- 摘要:
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【摘要】构建慢性肢体威胁性缺血(chronic limb-threatening ischemia,CLTI)动物模型旨在研究CLTI病程中病理生理变化,寻找更有效的治疗手段。近年随着临床治疗进展,动物实验模型研究得以进一步完善和发展。目前广泛应用的CLTI动物模型包括啮齿动物(如大鼠和小鼠)和大型动物(如兔和猪)。建立慢性缺血动物模型的方法包括结扎切除法、动脉电凝法、Ameroid环缩器以及腔内方法。该文就CLTI动物模型研究领域近年来主要进展做一综述,以便更清晰地了解不同动物和实验方法的优缺点,从而完善动物模型,为CLTI患者提供更好的治疗方案。
参考文献/References:
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备注/Memo
- 备注/Memo:
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(收稿日期:2024-05-07)
(本文编辑:谷珂)
更新日期/Last Update:
2025-03-25