[1]钟波,张桃梅,王志强,等.奇神经节持续射频与高电压长时程脉冲射频治疗直肠癌会阴痛临床研究[J].介入放射学杂志,2025,34(02):154-159.
 ZHONG Bo,ZHANG Taomei,WANG Zhiqiang,et al.Continuous radiofrequency versus high-voltage,long-duration pulsed radiofrequency of ganglia impar for the treatment of perineal pain in patients with rectal cancer:a clinical study[J].journal interventional radiology,2025,34(02):154-159.
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奇神经节持续射频与高电压长时程脉冲射频治疗直肠癌会阴痛临床研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
34
期数:
2025年02
页码:
154-159
栏目:
非血管介入
出版日期:
2025-02-17

文章信息/Info

Title:
Continuous radiofrequency versus high-voltage,long-duration pulsed radiofrequency of ganglia impar for the treatment of perineal pain in patients with rectal cancer:a clinical study
作者:
钟波张桃梅王志强陶平王怀明张爱民
Author(s):
ZHONG BoZHANG TaomeiWANG ZhiqiangTAO PingWANG HuaimingZHANG Aimin.
Department of Anesthesiology,Yanjiang District People′s Hospital,Ziyang,Sichuan Province 641399,China
关键词:
【关键词】奇神经节射频热凝脉冲射频会阴痛癌痛DSA引导
文献标志码:
A
摘要:
【摘要】目的评价DSA引导下奇神经节持续射频(CRF)与高电压长时程脉冲射频(HL-PRF)治疗直肠癌会阴痛的近期有效性和安全性。方法采用单中心、随机、主动对照、双盲试验法,根据射频治疗模式将57例直肠癌伴会阴痛患者以1∶1比例随机分为CRF组(n=28)和HL-PRF组(n=29)。主要结局指标为术前(T0),术后24 h(T1)、1周(T2)、1个月(T3)、3个月(T4)、6个月(T5)时点会阴部疼痛数字评价量表(NRS)评分;次要结局指标为T0、T1、T2、T3、T4、T5时点坐姿时间、9项患者健康问卷(PHQ-9)评分、Pittsburgh睡眠质量指数(PSQI)评分、术后口服吗啡剂量及会阴部麻木发生率。结果
与T0时点相比,两组患者T1~T5时点NRS评分、PHQ-9评分及PSQI评分显著下降,坐姿时间显著增加(均P<0.05),术后口服吗啡剂量和会阴部麻木发生率差异无统计学意义(均P>0.05)。与CRF组相比,HL-PRF组T1~T3时点NRS评分、PHQ-9评分、PSQI评分、坐姿时间及术后口服镇痛药物等差异无统计学意义(均P>0.05);T4~T5时点NRS评分、PHQ-9评分、PSQI评分显著增加(均P<0.05),坐姿时间显著降低(P<0.05)。结论奇神经节CRF和HL-PRF均能改善晚期直肠癌患者癌痛伴会阴痛,并提高其生活质量。但CRF长期疗效优于HL-PRF。

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备注/Memo

备注/Memo:
(收稿日期:2024-06-05)
(本文编辑:谷珂)
更新日期/Last Update: 2025-02-17