[1]李宝福,刘冰,王春满,等.脉冲射频联合神经阻滞治疗对顽固性带状疱疹后神经痛患者SF-MPQ评分及血清P物质、IL-1β水平的影响[J].介入放射学杂志,2024,33(11):1197-1202.
 LI Baofu,LIU Bing,WANG Chunman,et al.Effect of pulsed radiofrequency combined with nerve block on SF-MPQ score,levels of serum substance P and IL-1β in patients with refractory postherpetic neuralgia[J].journal interventional radiology,2024,33(11):1197-1202.
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脉冲射频联合神经阻滞治疗对顽固性带状疱疹后神经痛患者SF-MPQ评分及血清P物质、IL-1β水平的影响()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年11
页码:
1197-1202
栏目:
非血管介入
出版日期:
2024-11-20

文章信息/Info

Title:
Effect of pulsed radiofrequency combined with nerve block on SF-MPQ score,levels of serum substance P and IL-1β in patients with refractory postherpetic neuralgia
作者:
李宝福刘冰王春满李琳高谦
Author(s):
LI BaofuLIU BingWANG ChunmanLI LinGAO Qian.
Pain Department,Hengshui Municipal People′s Hospital (Harrison International Peace Hospital),Hengshui,Hebei Province 053000,China
关键词:
【关键词】带状疱疹后神经痛脉冲射频神经阻滞简式McGill疼痛问卷表P物质白细胞介素-6生活质量
文献标志码:
A
摘要:
【摘要】目的探讨脉冲射频联合神经阻滞治疗对顽固性带状疱疹后神经痛(PHN)患者简式McGill疼痛问卷表(SF-MPQ)评分及血清P物质、白细胞介素(IL)-1β水平的影响。方法选取2021年4月至2022年4月衡水市人民医院收治的219例PHN患者为研究对象,根据随机数表法均分为A组(73例)、B组(73例)和C组(73例),A组PHN患者接受神经脉冲射频治疗,B组PHN患者接受神经阻滞治疗,C组PHN患者接受神经阻滞联合神经脉冲射频治疗,比较各组患者SF-MPQ评分、血清P物质、IL-1β水平、焦虑抑郁情况、生活质量变化情况。结果219例PHN患者中因失访、研究期间转为其他方式治疗脱落6例,最终A组入组71例、B组入组70例、C组入组72例。治疗后7 d(AT7)、30 d(AT30)和90 d(AT90)时,C组PHN患者SF-MPQ疼痛分级指数评定(PRI)评分、视觉模拟评分法(VAS)评分、现时疼痛强度评定(PPI)评分均低于A组、B组(P<0.05),血清P物质、IL-1β水平均低于A组、B组(P<0.05),健康问卷抑郁量表(PHQ9)评分、广泛性焦虑量表(DAG7)评分、综合评定问卷(GQOL-74)评分均低于A组、B组(P<0.05)。结论脉冲射频联合神经阻滞用于顽固性PHN治疗能有效降低患者疼痛和血清P物质、IL-1β水平,缓解患者的焦虑、抑郁情绪,提高生活质量。

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备注/Memo

备注/Memo:
(收稿日期:2023-11-21)
(本文编辑:茹实)
更新日期/Last Update: 2024-11-20