[1]高谦,李宝福,刘冰,等.脉冲射频联合神经阻滞治疗顽固性带状疱疹神经痛的疗效[J].介入放射学杂志,2024,33(10):1083-1087.
 GAO Qian,LI Baofu,LIU Bing,et al.Curative effect of pulsed radiofrequency combined with nerve block for the treatment of refractory postherpetic neuralgia[J].journal interventional radiology,2024,33(10):1083-1087.
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脉冲射频联合神经阻滞治疗顽固性带状疱疹神经痛的疗效()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年10
页码:
1083-1087
栏目:
非血管介入
出版日期:
2024-10-21

文章信息/Info

Title:
Curative effect of pulsed radiofrequency combined with nerve block for the treatment of refractory postherpetic neuralgia
作者:
高谦李宝福刘冰王春满李琳
Author(s):
GAO QianLI BaofuLIU BingWANG ChunmanLI Lin.
Department of Pain Management,Hengshui Municipal People′s Hospital (Harrison International Peace Hospital),Hengshui,Hebei Province 053000,China
关键词:
【关键词】带状疱疹神经痛脉冲射频治疗神经阻滞治疗疗效
文献标志码:
A
摘要:
【摘要】目的探讨脉冲射频联合神经阻滞治疗顽固性带状疱疹后神经痛(postherpetic neuralgia,PHN)的疗效。方法选取2020年3月至2023年3月衡水市人民医院收治的PHN患者201例,按随机数表法均分为脉冲射频组、神经阻滞组和联合组,每组各67例。3组PHN患者均常规药物治疗,脉冲射频组采取神经脉冲射频治疗,神经阻滞组采取神经阻滞治疗,联合组经神经阻滞治疗后再采取神经脉冲射频治疗。观察治疗前(T0)、治疗后7 d(AT7)、治疗后30 d(AT30)和治疗后90 d(AT90)时PHN患者简式McGill疼痛问卷表(SF-MPQ)、匹兹堡睡眠质量指数(PSQI)、β-内啡肽、P物质、降钙素基因相关肽(CGRP)、肿瘤坏死因子(TNF)-α、白细胞介素(IL)-6变化,记录患者不良反应情况。结果AT7、AT30、AT90时,联合组PHN患者SF-MPQ的PRI、VAS、PPI评分和PSQI评分、P物质、CGRP、TNF-α、IL-6水平均低于脉冲射频组和神经阻滞组(P<0.05),β-内啡肽水平高于脉冲射频组和神经阻滞组(P<0.05),3组PHN患者在治疗过程中均无明显不良反应发生。结论脉冲射频联合神经阻滞治疗对顽固性PHN患者的疼痛、睡眠质量改善效果优于其单独治疗,可能与调节疼痛介质水平和炎性因子水平有关。

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备注/Memo

备注/Memo:
(收稿日期:2023-10-11)
(本文编辑:新宇)
更新日期/Last Update: 2024-10-17