[1]李如春,胡继红,潘文秋,等.TIPS治疗肝硬化伴或不伴门静脉血栓临床对比研究[J].介入放射学杂志,2024,33(10):1101-1106.
LI Ruchun,HU Jihong,PAN Wenqiu,et al.TIPS for the treatment of cirrhosis with or without portal vein thrombosis:a comparative study[J].journal interventional radiology,2024,33(10):1101-1106.
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TIPS治疗肝硬化伴或不伴门静脉血栓临床对比研究()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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33
- 期数:
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2024年10
- 页码:
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1101-1106
- 栏目:
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临床研究
- 出版日期:
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2024-10-21
文章信息/Info
- Title:
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TIPS for the treatment of cirrhosis with or without portal vein thrombosis:a comparative study
- 作者:
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李如春; 胡继红; 潘文秋; 卓松波; 张玉博; 田梽甫
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- Author(s):
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LI Ruchun; HU Jihong; PAN Wenqiu; ZHUO Songbo; ZHANG Yubo; TIAN Zhifu.
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Department of Medical Imaging,First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan Province 650032,China
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- 关键词:
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【关键词】肝硬化; 门静脉血栓形成; 消化道出血; 经颈静脉肝内门体分流术
- 文献标志码:
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A
- 摘要:
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【摘要】目的分析TIPS治疗肝硬化伴或不伴门静脉血栓形成(portal vein thrombosis,PVT)的临床特点及疗效。方法回顾性分析2018年10月至2022年10月在昆明医科大学第一附属医院接受TIPS治疗的肝硬化伴消化道出血患者193例,按术前有无PVT分为非PVT组118例,PVT组75例。分别于术后1、3、6个月及之后每6个月随访,观察PVT对肝硬化患者临床特征及TIPS术后疗效的影响。结果两组患者手术成功率均为100%。PVT组行脾脏切除或行分脾动脉栓塞术占26.7%(20/75),高于非PVT组的13.6%(16/118),差异有统计学意义(χ2=5.192,P=0.023)。PVT组患者术前Child-Pugh评分、MELD评分和MELD-Na+评分分别为(8.1±1.9)分、(9.2±8.0)分、(9.2±8.0)分,均高于非PVT组的(7.4±1.9)分、(7.7±5.8)分、(7.7±5.8)分,差异有统计学意义(P<0.05)。PVT组显性肝性脑病发生率33.3%(25/75)高于非PVT组19.5%(23/118),差异有统计学意义(P=0.030)。而术后生存率、再出血率和支架失功能率,两组差异无统计学意义(P>0.05)。结论TIPS用于治疗肝硬化PVT伴消化道出血安全、有效;PVT患者的肝功能更差,TIPS术后显性肝性脑病发生率更高。
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备注/Memo
- 备注/Memo:
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(收稿日期:2023-11-02)
(本文编辑:新宇)
更新日期/Last Update:
2024-10-17