[1]林志鹏,胡小龙,黄大钡,等.微波消融联合经皮骨成形术治疗扁骨转移瘤的临床疗效评价[J].介入放射学杂志,2024,33(09):976-982.
 LIN Zhipeng,HU Xiaolong,HUANG Dabei,et al.Evaluation of the clinical efficacy of microwave ablation combined with percutaneous osteoplasty in the treatment of flat bone metastases[J].journal interventional radiology,2024,33(09):976-982.
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微波消融联合经皮骨成形术治疗扁骨转移瘤的临床疗效评价()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年09
页码:
976-982
栏目:
非血管介入
出版日期:
2024-09-17

文章信息/Info

Title:
Evaluation of the clinical efficacy of microwave ablation combined with percutaneous osteoplasty in the treatment of flat bone metastases
作者:
林志鹏胡小龙黄大钡邹旭公陈源朱康顺张健李晓群
Author(s):
LIN ZhipengHU XiaolongHUANG DabeiZOU XugongCHEN YuanZHU KangshunZHANG JianLI Xiaoqun. Department of Interventional MedicineZhongshan Municipal People′s HospitalZhongshanGuangdong Province 528499China
(收稿日期:2023-08-17)(本文编辑:茹实)
关键词:
【关键词】微波消融骨成形术扁骨转移瘤
文献标志码:
A
摘要:
【摘要】目的评估微波消融联合经皮骨成形术(POP)治疗扁骨转移瘤的临床疗效、安全性及效价比。方法纳入2016年1月至2023年1月在中山市人民医院行微波消融联合POP(联合治疗)及单纯POP治疗的57例扁骨转移瘤伴顽固性疼痛患者,其中联合治疗组36例,单纯POP治疗组21例。采用视觉模拟量表(VAS)评分、Oswestry功能障碍指数(ODI)评分 、生活质量评价表(QOL)评分定期评价术前及术后不同时期的疗效,并进行两组比较,观察两组相关并发症发生情况。结果57例手术成功率100%,术后无严重手术并发症发生。随访(4.7±1.3)个月(3.4~7.2个月)。术前、术后1 d、1周、1个月及3个月VAS评分,联合组分别为(7.39±1.09)、(6.53±1.17)、(1.94±0.70)、(1.11±0.66)、(1.39±0.59)分,单纯POP组分别为(7.52±1.01)、(6.81±0.66)、(3.38±0.65)、(2.33±0.56)、(2.52±0.50)分;术后1周联合组VAS评分下降了(5.44±1.32)分,单纯POP组下降了(4.14±0.96)分;术后各随访点VAS评分两组间比较,术后1周(t=-7.62、P<0.01)、术后1个月(t=-7.28、P<0.01)、术后3个月(t=-7.58、P<0.01),差异均有统计学意义。术前、术后1 d、1周、1个月及3个月ODI评分,联合组分别为(44.33±2.91)、(44.08±2.82)、(15.92±3.04)、(14.00±2.39)、(16.08±3.61)分,单纯POP组分别为(45.67±3.03)、(45.14±2.80)、(22.38±3.09)、(19.76±2.99)、(22.10±3.10)分;术后1周联合组ODI评分平均下降了(28.42±4.23)分,单纯POP组下降了(23.29±4.28);术后各随访点ODI评分两组间比较,术后1周(t=-7.50、P<0.01)、术后1个月(t=-7.37、P<0.01)、术后3个月(t=-6.51、P<0.01),差异均有统计学意义。术前、术后1 d、1周、1个月及3个月QOL评价,联合组分别为(24.69±3.92)、(26.06±3.05)、(38.67±3.00)、(40.25±3.42)、(39.58±3.99)分,单纯POP组分别为(24.43±3.53)、(26.76±3.05)、(32.81±2.17)、(33.95±2.68)、(31.19±4.27)分,术后1周联合组QOL评分上升了(13.97±4.88)分,单纯POP组上升了(8.38±4.50)分;术后各随访点QOL评分两组间比较,术后1周(t=8.34、P<0.01)、术后1个月(t=7.56、P<0.01)、术后3个月(t=7.18、P<0.01),差异均有统计学意义。联合组的手术费用比单纯POP组平均高10 480.43元。结论单纯POP和微波消融联合POP治疗扁骨转移瘤均安全有效,可显著缓解疼痛,并提高患者生活质量。与单纯POP相比,联合治疗效果更好,但耗费也更高。

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备注/Memo

备注/Memo:
(收稿日期:2023-08-17)
(本文编辑:茹实)
更新日期/Last Update: 2024-09-15