[1]朱永新,张颖,徐晓东.衰弱状态与老年冠心病患者PCI术后心功能及其预后 [J].介入放射学杂志,2024,33(08):834-838.
 ZHU Yongxin,ZHANG Ying,XU Xiaodong..Correlation between the frailty status and myocardial injury in elderly patients with coronary heart disease after percutaneous coronary intervention[J].journal interventional radiology,2024,33(08):834-838.
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衰弱状态与老年冠心病患者PCI术后心功能及其预后
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年08
页码:
834-838
栏目:
心脏介入
出版日期:
2024-08-12

文章信息/Info

Title:
Correlation between the frailty status and myocardial injury in elderly patients with coronary heart disease after percutaneous coronary intervention
作者:
朱永新张颖徐晓东
Author(s):
ZHU YongxinZHANG YingXU Xiaodong.
Department of Cardiology,Chizhou Municipal People′s Hospital,Chizhou,Anhui Province 247000,China
关键词:
【关键词】冠心病 经皮冠脉介入术 Tilburg 衰弱量表 心肌损伤 心脏结构功能
文献标志码:
A
摘要:
【摘要】目的分析老年冠心病患者经皮冠脉介入治疗(PCI)后的衰弱状态与心肌损伤、心脏结构功能的关系,并评估其对长期预后的价值。 方法纳入2020年1月至2022年1月在安徽省池州市人民医院行 PCI的老年冠心病患者348例。术后通过改良Tilburg 衰弱量表进行评估,将总分≥5分的患者设置为衰弱组(n=152),其他患者为非衰弱组(n=196)。比较两组患者手术前后的心肌损伤标志物[B型利钠肽(BNP)、心肌肌钙蛋白T(cTnT)、 肌酸激酶同工酶(CK-MB)]和心功能指标[左心室收缩末内径(LVESD)、左心室舒张末内径(LVEDD)、左心室后壁厚度(LVPW)、左心室射血分数(LVEF)]。随访2年,对比两组发生心血管不良事件的情况(心源性休克、心源性死亡、严重心力衰竭、急性心肌梗死)。通过Pearson相关性分析患者心肌损伤及心脏结构功能与衰弱状态的关系,ROC曲线评估Tilburg评分对患者预后情况的诊断效能。 结果术后非衰弱组心肌损伤标志物水平、LVESD、LVEDD低于衰弱组,LVEF高于衰弱组(均P<0.05)。Tilburg评分与心肌损伤情况、LVESD、LVEDD呈正相关,与LVEF呈负相关;且Tilburg评分对患者预后评估的ROC曲线下面积为0.982。 结论老年冠心病患者PCI术后衰弱状态与心肌损伤及心脏结构功能有显著的相关性,对长期预后有较高的预测价值。

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备注/Memo

备注/Memo:
(收稿日期:2024-01-17)
(本文编辑:新宇)
更新日期/Last Update: 2024-08-08