[1]周腾超,龙 林,孙 林,等.载药微球对比传统化疗栓塞治疗分支门脉癌栓肝癌的临床研究[J].介入放射学杂志,2024,33(06):616-622.
 ZHOU Tengchao,LONG Lin,SUN Lin,et al.Drug-eluting beads versus conventional chemoembolization for liver cancer with branch portal vein tumor thrombus: a clinical study[J].journal interventional radiology,2024,33(06):616-622.
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载药微球对比传统化疗栓塞治疗分支门脉癌栓肝癌的临床研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年06
页码:
616-622
栏目:
肿瘤介入
出版日期:
2024-06-20

文章信息/Info

Title:
Drug-eluting beads versus conventional chemoembolization for liver cancer with branch portal vein tumor thrombus: a clinical study
作者:
周腾超 龙 林 孙 林 龙 瑶
Author(s):
ZHOU Tengchao LONG Lin SUN Lin LONG Yao.
Department of Interventional Vascular Surgery, First Affiliated Hospital of Hunan Normal University (Hunan Provincial People’s Hospital), Changsha, Hunan Province 410002, China
关键词:
【关键词】 经导管动脉内化疗栓塞 载药微球 碘油 分支门脉癌栓 疗效
文献标志码:
A
摘要:
【摘要】 目的 对比不同经导管动脉内化疗栓塞(TACE)方式应用于分支门脉癌栓(PVTT)肝细胞癌(HCC)患者的疗效及安全性。方法 回顾性纳入自2019年12月至2022年8月符合纳排标准的122例有分支PVTT的HCC患者,根据不同的TACE方式分为载药微球组(DEB-TACE)和传统TACE组(cTACE)。通过比较两组患者术后并发症、疼痛来评估两者的安全性。比较两组患者术后1个月的肿瘤反应率、术后的无进展生存时间(PFS)和总体生存时间(OS),探究哪一种TACE方式对有分支PVTT的HCC患者疗效更优。结果 两组的术后疼痛分级和并发症发生率基本无差异。TACE后1个月,DEB-TACE组的ORR(P=0.033)及DCR(P=0.096)优于cTACE组。DEB-TACE组和cTACE组的中位PFS分别为10.5个月及6.4个月(P=0.003),中位OS为19.3个月及16.8个月(P=0.019)。结论 TACE应用于分支PVTT的HCC患者是有效、安全的,DEB-TACE的术后疗效优于cTACE。为提高这部分患者的预后,我们更应该推荐DEB-TACE作为初次介入治疗的方式。

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备注/Memo

备注/Memo:

(收稿日期:2023- 06- 16)

(本文编辑:茹 实)

更新日期/Last Update: 2024-06-20