[1]杨崇明,吴文涛.深度镇静下肝癌微波消融术中镇静相关不良事件发生率及危险因素分析[J].介入放射学杂志,2023,32(12):1202-1206.
YANG Chongming,WU Wentao..Incidence of sedation-related adverse events during microwave ablation of liver cancer under deep sedation and analysis of its risk factors[J].journal interventional radiology,2023,32(12):1202-1206.
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深度镇静下肝癌微波消融术中镇静相关不良事件发生率及危险因素分析()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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32
- 期数:
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2023年12
- 页码:
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1202-1206
- 栏目:
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非血管介入
- 出版日期:
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2024-01-02
文章信息/Info
- Title:
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Incidence of sedation-related adverse events during microwave ablation of liver cancer under deep sedation and analysis of its risk factors
- 作者:
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杨崇明; 吴文涛
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- Author(s):
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YANG Chongming; WU Wentao.
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Department of Interventional Radiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210029, China
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- 关键词:
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【关键词】 深度镇静; 肝癌微波消融; 镇静相关不良事件; 危险因素
- 文献标志码:
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A
- 摘要:
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【摘要】 目的 分析深度镇静下行肝癌经皮穿刺微波消融术(PMWA)中与镇静相关不良事件的发生率,以及低氧血症、高血压、体动反应危险因素。方法 回顾性分析2018年12月至2022年12月在南京医科大学第一附属医院接受择期深度镇静下PMWA治疗的506例肝癌患者病历资料。记录术中深度镇静相关不良事件低氧血症、低血压、高血压及体动反应。采用单因素和多因素logistic回归分析评估低氧血症、高血压及体动反应的危险因素。结果 排除20例数据缺乏患者,最终研究样本由486例患者组成。深度镇静后5例(1%)患者出现低血压,低氧血症、高血压、体动反应发生率分别为13.8%、13.2%、25.5%。无患者需紧急气管插管,无心血管并发症发生,体动反应未增加消融并发症。多因素分析显示,年龄≥65岁(OR=1.034,P=0.033)、体质量指数(BMI)>30 kg/m2(OR=1.865,P=0.039)、肝功能Child-Pugh分级B/C级(OR=1.113,P=0.046)是低氧血症的危险因素,消融区接触壁层腹膜(OR=2.536,P<0.01)、消融区接触膈肌(OR=1.795,P=0.001)、消融区接触肾上腺(OR=1.581,P<0.01)是高血压的危险因素,消融区接触壁层腹膜(OR=2.831,P<0.01)、消融区接触膈肌(OR=2.213,P=0.026)是体动反应的危险因素。结论 深度镇静下行肝癌PMWA治疗安全有效。年龄≥65岁、BMI>30 kg/m2及Child-Pugh分级B/C级是低氧血症的危险因素,消融区接触壁层腹膜、膈肌、肾上腺是高血压的危险因素,消融区接触壁层腹膜、膈肌是体动反应的危险因素。
参考文献/References:
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备注/Memo
- 备注/Memo:
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(收稿日期:2023- 06- 02)
(本文编辑:谷 珂)
更新日期/Last Update:
2024-01-02