[1]林 佳,王龙飞,吴安乐,等.CT引导下注射吲哚菁绿在肺磨玻璃结节术前定位中的应用[J].介入放射学杂志,2023,32(06):556-559.
 LIN Jia,WANG Longfei,WU Anle,et al.The application of CT-guided intrapulmonary injection of indocyanine green in preoperative localization of pulmonary ground-glass nodules[J].journal interventional radiology,2023,32(06):556-559.
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CT引导下注射吲哚菁绿在肺磨玻璃结节术前定位中的应用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
32
期数:
2023年06
页码:
556-559
栏目:
非血管介入
出版日期:
2023-06-28

文章信息/Info

Title:
The application of CT-guided intrapulmonary injection of indocyanine green in preoperative localization of pulmonary ground-glass nodules
作者:
林 佳 王龙飞 吴安乐 滕 飞 咸玉涛 韩 瑞
Author(s):
LIN Jia WANG Longfei WU Anle TENG Fei XIAN Yutao HAN Rui.
Department of Interventional Radiology, Ningbo First Hospital, Ningbo, Zhejiang Province 315010, China
关键词:
【关键词】 吲哚菁绿 肺磨玻璃结节 定位 胸腔镜
文献标志码:
A
摘要:
【摘要】 目的 探讨CT引导下肺内注射吲哚菁绿(ICG)在肺磨玻璃结节(GGN)术前定位中的安全性和可行性。方法 回顾性分析2021年10月至2021年12月因发现肺结节就诊于宁波市第一医院胸外科,同时行CT引导下肺内注射ICG定位和电视胸腔镜(VATS)肺结节切除术患者的临床资料。记录结节定位、手术及病理等信息。评价定位成功率和并发症发生率。结果 共纳入64例患者(69枚GGN)。病灶直径为(0.7±0.3) cm,其中纯GGN 52个,混和GGN 17个。ICG定位时间为(9.3±4.1) min。并发症发生率为15.6%(10/64),5例少量气胸,5例少量肺内出血,均无特殊处理。术中所有结节均见荧光显影,2例见ICG弥散,但仍能找到病灶,定位成功率和手术切除成功率均达100%,无转开胸者,手术时间为(68.1±26.2) min,术中出血量为(12.0±5.2) mL。术后无严重并发症发生,术后住院时间(3.0±1.0) d,术后病理示肺腺癌91%(63/69)。结论 CT引导下肺内注射ICG定位肺GGN是安全有效的。

参考文献/References:

[1] 王 群.肺部磨玻璃结节的诊治策略[J]. 中国肺癌杂志, 2018, 21:160- 162.
[2] 胡 牧,崔 永. 肺部磨玻璃结节外科诊疗进展[J]. 中国肿瘤外科杂志, 2022, 14:6- 10.
[3] 潘 峰,刘 卓,袁 飞,等. 肺局限性磨玻璃结节的高分辨率CT征象与国际肺癌研究协会/美国胸科学会/欧洲呼吸学会病理的对照研究[J]. 中国医学影像学杂志, 2014:815- 819, 823.
[4] 王礼同,汤晓明,黄 华,等.电视胸腔镜手术前CT引导下亚甲蓝和/或Hookwire定位肺磨玻璃结节[J]. 中国医学影像技术,2019, 35:1220- 1223.
[5] Yeh YC,Kadota K,Nitadori J,et al. International Association for the Study of Lung Cancer /American Thoracic Society /European Respiratory Society classification predicts occultlymph node metastasis in clinically mediastinal node- negative lung adenocarcinoma[J]. Eur J Cardiothorac Surg, 2016, 49: 9- 15.
[6] Park CH, Han K, Hur J, et al. Comparative effectiveness and safety of preoperative lung localization for pulmonary nodules a systematic review and meta- analysis[J]. Chest, 2017, 151: 316- 328.
[7] 李明明,李 智,沈 健,等. 同步法Hook- wire多针定位在多发肺结节胸腔镜切除术中的应用[J]. 介入放射学杂志, 2020,29:1136- 1139.
[8] Cheng J,Li C,Wang L,et al. Precise localization of small pulmonary nodules using Pre- VATS with Xper- CT in combination with real- time fluoroscopy- guided coil: report of 15 patients[J]. J Interv Med, 2018, 1: 102- 105.
[9] 孟庆华,张 妺,胡效坤. CT引导下微弹簧圈与Hookwire在肺小结节穿刺定位中的应用比较[J]. 影像研究与医学应用, 2022, 6:179- 181.
[10] 倪慧霞,赵 卫,胡继红,等. CT引导下微弹簧圈定位在肺小结节胸腔镜术中的临床应用[J]. 介入放射学杂志, 2017, 26:555- 559.
[11] Kong J,Guo J,Zhang H,et al. CT- guided localization techniques of small pulmonary nodules:a prospective non- randomized controlled study on pulmonary nodule localization needle and methylene blue staining with surgical glue[J]. J Thorac Dis, 2020, 12: 6826- 6835.
[12] 钱 坤,张 毅,魏博华,等. 吲哚菁绿联合医用胶在胸腔镜下肺小结节手术定位中的应用[J]. 中国微创外科杂志, 2020, 20:818- 821.
[13] Li X,Xu K,Cen R,et al. Preoperative computer tomography- guided indocyanine green injection is associated with successful localization of small pulmonary nodules[J]. Transl Lung Cancer Res, 2021, 10: 2229- 2236.
[14] 曹 剑,王志伟,丁 宁,等. 吲哚菁绿在胸腔镜肺小结节手术定位中的应用价值[J]. 中国医学科学院学报, 2021, 43:558- 562.
[15] 王 冲,刘 洋,杨 磊,等. CT引导下术前经皮肺穿刺注射吲哚菁绿定位肺内小结节和磨玻璃结节有效性和安全性分析[J]. 中华医学杂志, 2020, 100:538- 540.
[16] Okusanya OT,Holt D,Heitjan D,et al. Intraoperative near- infrared imaging can identify pulmonary nodules[J]. Ann Thorac Surg, 2014, 98: 1223- 1230.
[17] 郭 晶,石建光,李晨蔚,等. 术前CT引导下Hook- wire定位肺部磨玻璃样结节在胸腔镜肺切除术中的临床研究[J]. 浙江临床医学, 2017, 19:646- 648.
[18] Hiraki T,Mimura H,Gobara H,et al. Incidence of and risk factors for pneumothorax and chest tube placement after CT fluoroscopy- guided percutaneous lung biopsy: retrospective analysis of the procedures conducted over a 9- year period[J]. AJR Am J Roentgenol, 2010, 194: 809- 814.
[19] Boskovic T,Stanic J,Pena- Karan S,et al. Pneumothorax after transthoracic needle biopsy of lung lesions under CT guidance[J]. J Thorac Dis, 2014, 6: S99- S107.
[20] Mao Y,Chi C,Yang F,et al. The identification of sub- centimetre nodules by near- infrared fluorescence thoracoscopic systems in pulmonary resection surgeries[J]. Eur J Cardiothorac Surg, 2017, 52: 1190- 1196.
[21] 陈克敏,黄 蔚,吴志远. CT引导下肺活检和并发症的预防[J]. 介入放射学杂志, 2011, 20:163- 165.
[22] 何 闯,李 扬,杨 丽,等. CT引导下肺实性结节切割活检术后出血与气胸的多因素分析[J]. 介入放射学杂志, 2017, 26:654- 659.
[23] 刘 丽,文 军,艾 敏,等. CT引导下弹簧圈联合亚甲蓝定位在周围型肺小结节电视胸腔镜手术中的应用[J]. 介入放射学杂志, 2018, 27:1168- 1172.
[24] Zhang H,Si T,Guo Z. Clinicopathologic characteristics of pulmonary ground glass opacity located preoperatively using a hook- wire guidewire[J]. J Interv Med, 2020, 3: 89- 92.

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 LI Xiangyang,MU Feng,CHEN Jibing,et al.CT-guided percutaneous cryoablation for the treatment of pulmonary ground- glass nodules[J].journal interventional radiology,2021,30(06):1072.

备注/Memo

备注/Memo:
(收稿日期:2022- 05- 09)
(本文编辑:新 宇)
更新日期/Last Update: 2023-06-26