[1]张学贤,杨 凯,冯超凡,等.颅内动脉瘤支架植入术后新生内膜增生临床研究[J].介入放射学杂志,2022,31(04):328-332.
 ZHANG Xuexian,YANG Kai,FENG Chaofan,et al.Clinical study of neointimal hyperplasia after stent implantation for intracranial aneurysms[J].journal interventional radiology,2022,31(04):328-332.
点击复制

颅内动脉瘤支架植入术后新生内膜增生临床研究()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
31
期数:
2022年04
页码:
328-332
栏目:
神经介入
出版日期:
2022-06-15

文章信息/Info

Title:
Clinical study of neointimal hyperplasia after stent implantation for intracranial aneurysms
作者:
张学贤 杨 凯 冯超凡 万 程 赵 卫 胡继红 孟雪柔 李自恒
Author(s):
ZHANG Xuexian YANG Kai FENG Chaofan WAN Cheng ZHAO Wei HU Jihong MENG Xuerou LI Ziheng.
Department of Medical Imaging, First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province 650032, China
关键词:
【关键词】 颅内动脉瘤 支架 新生内膜增生
文献标志码:
A
摘要:
【摘要】 目的 探讨颅内动脉瘤支架植入术后新生内膜增生(NIH)变化及其影响因素。方法 收集2018年10月至2020年10月在昆明医科大学第一附属医院接受支架辅助弹簧圈栓塞(SACE)或血流导向装置(FD)治疗的42例颅内前循环动脉瘤患者临床资料。分析治疗后支架NIH状况及影响因素。两名高年资神经介入医师根据血管造影图像,测量并记录患者术后即刻、术后随访复查时支架段最狭窄处、颈内动脉岩段直径,并计算每幅图像比率(T值,支架段直径/岩段颈内动脉直径)。 结果 T值变化呈由大至小再由小变大的动态过程,远期随访10~15个月(中位12.5个月)T值已基本恢复至术后即刻水平。单因素分析结果显示年龄、动脉瘤长径是患者中期NIH的影响因素。多因素logistic回归分析显示年龄是中期NIH发生的预测因子(OR=0.903,95%CI=0.828~0.984,P=0.020),患者年龄越大治疗后出现NIH的可能性越小。结论 颅内动脉瘤支架植入术后NIH变化是一逐渐加重、逐渐减轻的动态过程,远期随访时支架段血管直径基本恢复至术后即刻水平。年龄、动脉瘤大小是患者中期NIH影响因素,年龄是独立保护因素。

参考文献/References:

[1] Kim YS, Lee SW, Yeom JA, et al. Angiographic findings of in-stent intimal hyperplasia after stent- assisted coil embolization: are they permanent findings?[J]. J Neurosurg, 2016, 124: 328-333.
[2] Wakhloo AK, Gounis MJ. Revolution in aneurysm treatment: flow diversion to cure aneurysms: a paradigm shift[J]. Neurosurgery, 2014, 61(Suppl 1): 111-120.
[3] John S, Bain MD, Hui FK, et al. Long- term follow- up of in- stent stenosis after pipeline flow diversion treatment of intracranial aneurysms[J]. Neurosurgery, 2016, 78: 862-867.
[4] 《药学与临床研究》编辑部. 如何正确运用组内相关系数进行一致性检验——药物研究中的统计学(一) [J]. 药学与临床研究, 2018, 26:7-8.
[5] 蒋业清,鲁 刚,葛 亮,等. 颅内动脉瘤介入治疗相关症状性缺血并发症分析[J]. 介入放射学杂志, 2021, 30:112-117.
[6] Kuhn AL, Kan P, Srinivasan V, et al. Flow diverter for endovascular treatment of intracranial nirror segment internal carotid artery aneurysms[J]. Interv Neuroradiol, 2019, 25: 4-11.
[7] Kuhn AL, Hou SY, Perras M, et al. Flow diverter stents for unrup- tured saccular anterior circulation perforating artery aneurysms: safety, efficacy, and short- term follow- up[J]. J Neurointerv Surg, 2015, 7: 634- 640.
[8] Guzzardi G, Stanca C, Cerini P, et al. Long- term follow- up in the endovascular treatment of intracranial aneurysms with flow-diverter stents: update of a single- centre experience[J]. Radiol Med, 2018, 123: 449-455.
[9] 嵇再雄,李家祺,王建波. 酸枣仁皂苷B通过调节自噬抑制血小板衍生生长因子-BB诱导的血管平滑肌细胞增殖和迁移[J]. 介入放射学杂志, 2021, 30:149-152.
[10] Cohen JE, Gomori JM, Moscovici S, et al. Delayed complications after flow- diverter stenting: reactive in- stent stenosis and creeping stents[J]. J Clin Neurosci, 2014, 21: 1116-1122.
[11] Caroff J, Iacobucci M, Rouchaud A, et al. The occurrence of neointimal hyperplasia after flow- diverter implantation is associated with cardiovascular risks factors and the stent design[J]. J Neurointerv Surg, 2019, 11: 610- 613.
[12] Thomas AJ, Ogilvy CS. Flow diversion for intracranial aneurysm treatment[J]. Neurosurgery, 2020, 86(Suppl 1): S1-S2.
[13] Chalouhi N, Daou B, Kung D, et al. Fate of the ophthalmic artery after treatment with the pipeline embolization device[J]. Neurosurgery, 2015, 77: 581-584.
[14] Feng X, Qian Z, Liu P, et al. Comparison of recanalization and in- stent stenosis between the low- profile visualized intraluminal support stent and enterprise stent-assisted coiling for 254 intracranial aneurysms[J]. World Neurosurg, 2018, 109: e99- e104.
[15] Sindeev S, Prothmann S, Frolov S, et al. Intimal hyperplasia after aneurysm treatment by flow diversion[J]. World Neurosurg, 2019, 122: e577- e583.

相似文献/References:

[1]谢苏庆,许国铭.治疗门脉高压的新途径——经颈静脉肝内门体分流术[J].介入放射学杂志,1994,(02):116.
[2]陈云燕.TIPSS的并发症[J].介入放射学杂志,1994,(03):174.
[3]祖茂衡,徐浩,顾玉明,等.血管内支架放置治疗下腔静脉闭塞伴血栓形成[J].介入放射学杂志,1995,(04):195.
[4]王永杰,王洪明,王向阳,等.血管内支架置入术治疗下腔静脉阻塞[J].介入放射学杂志,1995,(04):198.
[5]金惠根,王肖龙,陆志刚,等.冠脉内支架在冠脉病变中的应用价值[J].介入放射学杂志,1999,(02):12.
[6]徐仲英.地塞米松血管内支架影响内膜增生的实验研究[J].介入放射学杂志,2000,(02):98.
[7]黄连军,蒋世良,赵世华,等.JOSTENT支架在治疗主动脉及外周动脉狭窄疾患中的应用[J].介入放射学杂志,2000,(02):73.
[8]何仕诚,滕皋军,郭金和,等.自制Palmaz支架的动物实验研究[J].介入放射学杂志,2000,(03):174.
[9]刘增品,赵林,王铁刚,等.颅内静脉窦狭窄支架成型术一例[J].介入放射学杂志,2006,(01):63.
 LIU Zeng-pin,ZHAO Lin,WANG Tie-gang,et al.Endovascular stenting for intracranial venous stenosis(a report of 1 case)[J].journal interventional radiology,2006,(04):63.
[10]纪东华,王峰,李城,等.经肝胃造瘘胃肠道支架成形术[J].介入放射学杂志,2006,(03):160.
 JI Dong-hua,WANG Feng,LI Cheng,et al.Gastrointestinal stenting:transhepatic and gastrostomy pathways[J].journal interventional radiology,2006,(04):160.
[11]黄海东,顾建文,杨春敏,等.Enterprise支架辅助弹簧圈栓塞治疗前交通宽颈动脉瘤的临床研究[J].介入放射学杂志,2012,(07):536.
 HUANG Hai- dong,GU Jian- wen,YANG Chun-min,et al. Enterprise stent- assisted coil embolization for wide?蛳 necked anterior communicating artery aneurysms: a clinical study[J].journal interventional radiology,2012,(04):536.
[12]田红岸,赵 卫,易根发. 颅内动脉瘤内支架辅助治疗的并发症分析[J].介入放射学杂志,2012,(11):885.
 TIAN Hong- an,ZHAO Wei,YI Geng- fa.. Endovascular stent- assited management for the treatment of intracranial aneurysms: an analysis of complications[J].journal interventional radiology,2012,(04):885.
[13]崔艳峰,徐 浩,祖茂衡,等. Solitaire AB支架在辅助栓塞颅内宽颈动脉瘤中的临床应用[J].介入放射学杂志,2013,(08):617.
 CUl Yan? feng,XU Hao,ZU Mao? heng,et al. Clinical application of Solitaire AB stent in assisting coiling embolization for intracranial wide?蛳 necked aneurysms[J].journal interventional radiology,2013,(04):617.
[14]张祥海,陈金华,向建波,等. 双容积重建透明影像在颅内动脉瘤支架植入术中的应用[J].介入放射学杂志,2014,(06):466.
 ZHANG Xiang- hai,CHEN Jin- hua,XIANG Jian- bo,et al. Application of dual volume reconstruction translucent imaging in performing stent implantation for intracranial aneurysms[J].journal interventional radiology,2014,(04):466.
[15]陈 振,刘 朝,李冬冬,等.LVIS支架辅助栓塞颅内动脉瘤安全性及有效性分析 [J].介入放射学杂志,2017,(09):775.
 CHEN Zhen,LIU Chao,LI Dongdong,et al.LVIS stent- assisted endovascular embolization therapy for intracranial aneurysms: analysis of the safety and efficacy[J].journal interventional radiology,2017,(04):775.
[16]陈 蓦,王 武.颅内动脉瘤血管内治疗现状与进展[J].介入放射学杂志,2018,27(06):592.
 CHEN Mo,WANG Wu..Endovascular treatment of intracranial aneurysms: its current situation and progress[J].journal interventional radiology,2018,27(04):592.
[17]张鸿运,邵秋季,李 立,等.支架治疗颅内远端动脉瘤安全性和有效性分析[J].介入放射学杂志,2022,31(12):1146.
 ZHANG Hongyun,SHAO Qiuji,LI Li,et al.Stenting for intracranial distal aneurysms: analysis of its safety and efficacy[J].journal interventional radiology,2022,31(04):1146.

备注/Memo

备注/Memo:
(收稿日期:2021- 05- 08)
(本文编辑:边 佶)
更新日期/Last Update: 2022-05-11