[1]刘 剑,谢 勇,魏 翠,等.早期经颈静脉肝内门体分流术治疗肝硬化急性静脉曲张破裂出血患者的meta分析[J].介入放射学杂志,2022,31(01):19-26.
 LIU Jian,XIE Yong,WEI Cui,et al.The clinical value of early TIPS in treating cirrhotic patients with acute variceal rupture hemorrhage: a meta-analysis[J].journal interventional radiology,2022,31(01):19-26.
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早期经颈静脉肝内门体分流术治疗肝硬化急性静脉曲张破裂出血患者的meta分析()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
31
期数:
2022年01
页码:
19-26
栏目:
血管介入
出版日期:
2022-01-25

文章信息/Info

Title:
The clinical value of early TIPS in treating cirrhotic patients with acute variceal rupture hemorrhage: a meta-analysis
作者:
刘 剑 谢 勇 魏 翠 田 欢 向 斌 向 华
Author(s):
LIU Jian XIE Yong WEI Cui TIAN Huan XIANG Bin XIANG Hua.
Department of Interventional Vascular Surgery, First Affiliated Hospital of Hunan Normal University, Hunan Provincial People’s Hospital, Changsha, Hunan Province 410005, China
关键词:
【关键词】 经颈静脉肝内门体分流术 内镜治疗 肝硬化 静脉曲张 meta分析
文献标志码:
A
摘要:
【摘要】 目的 meta分析比较早期经颈静脉肝内门体分流术(TIPS)和内镜治疗(ET)对肝硬化急性静脉曲张破裂出血(AVB)患者的治疗价值。方法 检索中国知网、中国生物医学文献数据库(CBM)、万方数据库、PubMed、Web of Science、Cochrane Library数据库,纳入建库至2020年2月1日有关早期TIPS和ET治疗肝硬化AVB对照试验研究,采用Stata 16.0软件进行统计学处理。结果 共检索相关文献893篇,最终纳入6项研究,涉及1 806例患者,其中TIPS组424例,ET组1 382例。TIPS组控制肝硬化AVB患者5 d内出血显著低于ET组(Log OR=-2.00,95%CI=-2.89~-1.12,P<0.05;I2=0%,P=0.75),早期(5 d至6周)再出血显著低于ET组(Log OR=-1.47,95%CI=-1.99~-0.94,P<0.05;I2=0%,P=0.59),1年病死率显著低于ET组(Log OR=-0.69,95%CI=-1.32~-0.07,P=0.03;I2=52.79%,P=0.08),非严重并发症发生率较ET组低(Log OR=-0.89,95%CI=-1.62~-0.17,P=0.02;I2=0%,P=0.40)。结论 早期TIPS治疗肝硬化AVB患者的有效性和安全性均优于ET,可推荐用于治疗大部分肝硬化AVB患者。

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备注/Memo

备注/Memo:
(收稿日期:2020- 09- 24)
(本文编辑:边 佶)
更新日期/Last Update: 2022-01-12