[1]杨 凯,张学贤,赵 卫,等.经颈静脉肝内门体分流术后肝性脑病研究进展[J].介入放射学杂志,2021,30(11):1180-1183.
　YANG Kai,ZHANG Xuexian,ZHAO Wei,et al.Research progress in hepatic encephalopathy occurring after transjugular intrahepatic portosystemic shunt[J].journal interventional radiology,2021,30(11):1180-1183.
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经颈静脉肝内门体分流术后肝性脑病研究进展()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
30
期数:
2021年11
页码:
1180-1183
栏目:
综述
出版日期:
2021-11-25

文章信息/Info

Title:
Research progress in hepatic encephalopathy occurring after transjugular intrahepatic portosystemic shunt
作者:
杨 凯;  张学贤;  赵 卫;  王 飞;  陆 孜;  冯超凡;  熊 峰
Author(s):
YANG Kai;  ZHANG Xuexian;  ZHAO Wei;  WANG Fei;  LU Zi;  FENG Chaofan;  XIONG Feng
Department of Medical Imaging， First Affiliated Hospital of Kunming Medical University， Kunming， Yunnan Province 650032， China
关键词:
【关键词】 经颈静脉肝内门体分流术; 肝性脑病; 门静脉高压
文献标志码:
A
摘要:
【摘要】 经颈静脉肝内门体分流术（TIPS）已在临床上大规模应用。TIPS治疗肝硬化门静脉高压所致并发症效果显著，但术后肝性脑病（HE）发生率高。该文就TIPS术后HE发生机制、分型和分级、危险因素及治疗作一综述。

参考文献/References:

［1］ Rahimi RS， Rockey DC. Hepatic encephalopathy： how to test and treat［J］. Curr Opin Gastroenterol， 2014， 30： 265-271.
［2］ Fiati KS， Song X， Li Z， et al. Mechanistic insight， diagnosis， and treatment of ammonia-induced hepatic encephalopathy［J］. J Gastroenterol Hepatol， 2019， 34： 31-39.
［3］ Vozzo CF， Singh T， Bullen J， et al. Hospital readmission following transjugular intrahepatic portosystemic shunt： a 14-year single- center experience［J］. Gastroenterol Rep（Oxf）， 2020， 8： 98-103.
［4］ 中华医学会肝病学分会． 肝硬化肝性脑病诊疗指南（2018年，北京）［J］． 中华胃肠内镜电子杂志， 2018， 5：97-113．
［5］ Wijdicks EF. Hepatic encephalopathy［J］. N Engl J Med， 2016， 375： 1660-1670.
［6］ Said VJ， Garcia-Trujillo E. Beyond lactulose： treatment options for hepatic encephalopathy［J］. Gastroenterol Nurs， 2019， 42： 277-285.
［7］ Dellatore P， Cheung M， Mahpour NY， et al. Clinical manifes-tations of hepatic encephalopathy［J］. Clin Liver Dis， 2020， 24： 189-196.
［8］ Ferenci P， Lockwood A， Mullen K， et al. Hepatic encephalopathy：definition， nomenclature， diagnosis， and quantification： final report of the working party at the 11th World Congresses of Gas-troenterology， Vienna， 1998［J］. Hepatology， 2002， 35： 716-721.
［9］ Dhiman RK， Saraswat VA， Sharma BK， et al. Minimal hepatic encephalopathy： consensus statement of a working party of the Indian National Association for Study of the Liver［J］. J Gastro-enterol Hepatol， 2010， 25： 1029-1041.
［10］ 赵洪伟，刘福全，岳振东，等． 应用覆膜支架TIPS治疗不同类型慢性门静脉血栓术后肝性脑病发生探讨［J］． 介入放射学杂志， 2014， 23：672- 678．
［11］ Schindler P， Seifert L， Masthoff M， et al. TIPS modification in the management of shunt-induced hepatic encephalopathy： analysis of predictive factors and outcome with shunt modification［J］. J Clin Med， 2020， 9： 567.
［12］ Coronado WM， Ju C， Bullen J， et al. Predictors of occurrence and risk of hepatic encephalopathy after TIPS creation： a 15- year experience［J］. Cardiovasc Intervent Radiol， 2020， 43： 1156-1164.
［13］ Bai M， Qi X， Yang Z， et al. Predictors of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt in cirrhotic patients： a systematic review［J］. J Gastroenterol Hepatol， 2011， 26： 943-951.
［14］ Luo SH， Chu JG， Huang H， et al. Targeted puncture of left branch of intrahepatic portal vein in transjugular intrahepatic portosystemic shunt to reduce hepatic encephalopathy［J］. World J Gastroenterol， 2019， 25： 1088-1099.
［15］ Chen SL， Hu P， Lin ZP， et al. The effect of puncture sites of portal vein in TIPS with ePTFE- covered stents on postoperative long-term clinical efficacy［J］. Gastroenterol Res Pract， 2019， 2019：2935498.
［16］ Sturm L， Bettinger D， Giesler M， et al. Treatment with proton pump inhibitors increases the risk for development of hepatic encephalopathy after implantation of transjugular intrahepatic portosystemic shunt（TIPS）［J］. United European Gastroenterol J， 2018， 6：1380-1390.
［17］ Lewis DS， Lee TH， Konanur M， et al. Proton pump inhibitor use is associated with an increased frequency of new or worsening hepatic encephalopathy after transjugular intrahepatic portosystemic shunt creation［J］. J Vasc Interv Radiol， 2019， 30： 163-169.
［18］ Shi D， Zhou ZY， Dai Y， et al. Proton pump inhibitor therapy and hepatic encephalopathy risk in cirrhotic patients： a systematic review with meta-analysis［J］. Clin Drug Investig， 2019， 39： 847-856.
［19］ Gioia S， Merli M， Nardelli S， et al. The modification of quantity and quality of muscle mass improves the cognitive impairment after TIPS［J］. Liver Int， 2019， 39： 871-877.
［20］ Nardelli S， Lattanzi B， Merli M， et al. Muscle alterations are associated with minimal and overt hepatic encephalopathy in patients with liver cirrhosis［J］. Hepatology， 2019， 70： 1704-1713.
［21］ Bhanji RA， Moctezuma-Velazquez C， Duarte-Rojo A， et al. Myosteatosis and sarcopenia are associated with hepatic encepha-lopathy in patients with cirrhosis［J］. Hepatol Int， 2018， 12： 377-386.
［22］ Chang KV， Chen JD， Wu WT， et al. Is sarcopenia associated with hepatic encephalopathy in liver cirrhosis? A systematic review and meta-analysis［J］. J Formos Med Assoc， 2019， 118： 833-842.
［23］ Yin X， Zhang F， Xiao J， et al. Diabetes mellitus increases the risk of hepatic encephalopathy after a transjugular intrahepatic portosystemic shunt in cirrhotic patients［J］. Eur J Gastroenterol Hepatol， 2019， 31： 1264-1269.
［24］ Wang Z， Chu P， Wang W. Combination of rifaximin and lactulose improves clinical efficacy and mortality in patients with hepatic encephalopathy［J］. Drug Des Devel Ther， 2019， 13： 1-11.
［25］ Zacharias HD， Zacharias AP， Gluud LL， et al. Pharmaco-therapies that specifically target ammonia for the prevention and treatment of hepatic encephalopathy in adults with cirrhosis［J］. Cochrane Database Syst Rev， 2019， 6：CD012334.
［26］ Pereira K， Carrion AF， Salsamendi J， et al. Endovascular management of refractory hepatic encephalopathy complication of transjugular intrahepatic portosystemic shunt（TIPS）： comprehen-sive review and clinical practice algorithm［J］. Cardiovasc Intervent Radiol， 2016， 39： 170-182.
［27］ 李 岩，褚建国，邹显志，等． 可控弹簧圈限制TIPS分流道血流治疗难治性肝性脑病［J］． 中国介入影像与治疗学， 2019， 16：726-729．
［28］ Cookson DT， Zaman Z， Gordon-Smith J， et al. Management of transjugular intrahepatic portosystemic shunt（TIPS） - associated refractory hepatic encephalopathy by shunt reduction using the parallel technique： outcomes of a retrospective case series［J］. Cardiovasc Intervent Radiol， 2011， 34： 92-99.
［29］ Chung HH， Razavi MK， Sze DY， et al. Portosystemic pressure gradient during transjugular intrahepatic portosystemic shunt with Viatorr stent graft： what is the critical low threshold to avoid medically uncontrolled low pressure gradient related complica-tions?［J］. J Gastroenterol Hepatol， 2008， 23： 95-101.
［30］ 何创业，陈 辉，吕 勇，等． 限流支架治疗经颈静脉肝内门体分流术后复发性或持续性显性肝性脑病的效果和安全性［J］． 临床肝胆病杂志， 2019， 35：1719-1722．
［31］ 褚建国，孙晓丽，朴龙松，等． 限流支架植入治疗TIPS引起的难治性肝性脑病［J］． 空军总医院学报， 2002， 18：125-128．
［32］ 李锋东，高虹霞． 人工肝血浆置换联合血液滤过治疗肝衰竭伴肝性脑病患者的可行性［J］． 医疗装备， 2020， 33：67- 68．
［33］ 贾亚男，李 瀚，李先亮，等． 危重症肝病肝移植患者诊断和评估标准的临床进展［J］． 器官移植， 2020， 11：326-331．

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备注/Memo

备注/Memo:
（收稿日期：2020-05-20）
（本文编辑：边 佶）
更新日期/Last Update: 2021-11-22