[1]汪 磊,陈 佳,李志虎,等.髂内动脉化疗栓塞在极高危非肌层浸润性膀胱癌经尿道电切术后的应用及价值[J].介入放射学杂志,2020,29(10):988-992.
WANG Lei,CHEN Jia,LI Zhihu,et al.Application and clinical value of intra-arterial chemoembolization via internal iliac artery in treating extremely high-risk non-muscle invasive bladder cancer after trans-urethral resection[J].journal interventional radiology,2020,29(10):988-992.
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髂内动脉化疗栓塞在极高危非肌层浸润性膀胱癌经尿道电切术后的应用及价值()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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29
- 期数:
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2020年10
- 页码:
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988-992
- 栏目:
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肿瘤介入
- 出版日期:
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2020-10-25
文章信息/Info
- Title:
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Application and clinical value of intra-arterial chemoembolization via internal iliac artery in treating extremely high-risk non-muscle invasive bladder cancer after trans-urethral resection
- 作者:
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汪 磊; 陈 佳; 李志虎; 王 刚; 果宏峰; 张侃玺; 何 山; 李宁忱
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- Author(s):
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WANG Lei; CHEN Jia; LI Zhihu; WANG Gang; GUO Hongfeng; ZHANG Kanxi; HE Shan; LI Ningchen.
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Department of Urology, Shougang Hospital of Peking University, Wujieping Urology Center of Peking University, Beijing 100144, China
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- 关键词:
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【关键词】 极高危; 非肌层浸润性膀胱癌; 髂内动脉化疗栓塞术; 复发; 根治性膀胱切除
- 文献标志码:
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A
- 摘要:
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【摘要】 目的 极高危非肌层浸润性膀胱癌具有很高的复发和进展风险。明确双侧髂内动脉化疗栓塞术(IAC)经尿道电切术后辅助措施的价值。方法 回顾性分析2015年1月至2017年12月收治的该类患者38例,均接受经尿道膀胱肿瘤电切术及术后规律膀胱灌注治疗(卡介苗或表柔吡星/吡柔吡星),根据是否接受IAC分为IAC组及对照组。IAC组在电切术后2周内接受第1疗程IAC,再间隔3~4周行第2疗程IAC,化疗方案:顺铂60 mg/m2,吡柔比星25 mg/m2。术后随访指标包括无复发生存时间、随访期间进展率及切除膀胱率等。 结果 IAC组12例,对照组26例,平均随访时间 (30.1±12.4)个月。IAC组与对照组在主要观察指标上的比较如下:无复发生存时间 (20.3±14.1)个月比 (8.9±7.2)个月,(P=0.002),1年无复发生存率66.7%比26.9%,(P=0.02),2年无复发生存率33.3%比7.7%,(P=0.07),随访期间进展率33.3%比46.2%,(P=0.46),切除膀胱率25.0%比46.2%,(P=0.21)。结论 对于极高危非肌层浸润性膀胱癌患者,在经尿道电切术后辅助双侧髂内动脉化疗栓塞有助于延缓疾病的复发。
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备注/Memo
- 备注/Memo:
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(收稿日期:2019-12-22)
(本文编辑:俞瑞纲)
更新日期/Last Update:
2020-10-19