[1]谢明团,张 兴,刘 茜,等.血栓抽吸在急性ST段抬高型心肌梗死患者不同发病时段中应用的临床疗效[J].介入放射学杂志,2020,29(05):444-448.
XIE Mingtuan,ZHANG Xing,LIU Qian,et al.Clinical effect of thrombus aspiration performed at different time after onset of acute ST- segment elevation myocardial infarction[J].journal interventional radiology,2020,29(05):444-448.
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血栓抽吸在急性ST段抬高型心肌梗死患者不同发病时段中应用的临床疗效()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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29
- 期数:
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2020年05
- 页码:
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444-448
- 栏目:
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心脏介入
- 出版日期:
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2020-05-25
文章信息/Info
- Title:
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Clinical effect of thrombus aspiration performed at different time after onset of acute ST- segment elevation myocardial infarction
- 作者:
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谢明团; 张 兴; 刘 茜; 张玉珍; 谢 飞; 董 薇; 肖群林; 陈 静; 彭景添; 王梦洪; 郑泽琪; 彭小平
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- Author(s):
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XIE Mingtuan; ZHANG Xing; LIU Qian; ZHANG Yuzhen; XIE Fei; DONG Wei; XIAO Qunlin; CHEN Jing; PENG Jingtian; WANG Menghong; ZHENG Zeqi; PENG Xiaoping.
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Department of Cardiology, First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province 330006, China
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- 关键词:
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【关键词】 血栓抽吸; 急性ST段抬高型心肌梗死; 经皮冠状动脉介入治疗; 临床疗效
- 文献标志码:
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A
- 摘要:
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【摘要】 目的 分析急性ST段抬高型心肌梗死(STEMI)患者经皮冠状动脉介入治疗(PCI)中不同时段行血栓抽吸的临床效果。方法 选取2015年1月至2018年6月就诊于南昌大学第一附属医院并经冠状动脉造影诊断为高负荷血栓的STEMI患者127例作为研究对象。根据是否行血栓抽吸术,将患者分为血栓抽吸+PCI组(63例,A组)、常规PCI组(64例,B组)。根据发病开始至导丝通过犯罪血管时间≤6 h、>6 h且≤12 h、>12 h且≤24 h,A组又分为A1组(23例)、A2组(27例)、A3组(13例),B组又分为B1组(25例)、B2组(25例)、B3组(14例)。比较各组患者术后心肌梗死溶栓(TIMI)后血流分级、术后1 h ST段回落、术后7 d左心室射血分数(LVEF)、术后3个月主要心血管不良事件(MACE)发生。 结果 A组PCI术后TIMI血流分级达3级比例、术后1 h心电图相关导联ST段完全回落比例和术后7 d LVEF均优于B组(P<0.05)。A2组术后TIMI血流分级达3级比例优于B2组(P<0.05),A3组术后TIMI血流分级达3级比例、术后1 h ST段完全回落比例和术后7 d LVEF均优于B3组(P<0.05)。术后3个月A组与B组、A1组与B1组、A2组与B2组、A3组与B3组间MACE发生率差异均无统计学意义(P>0.05)。 结论 高血栓负荷STEMI患者PCI术中联合血栓抽吸,有利于减少无复流或慢血流发生,提高术后心肌灌注水平,改善左心室功能,尤其是在心肌缺血12~24 h内,可减少心肌缺血时间延长对心脏的损害。
参考文献/References:
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备注/Memo
- 备注/Memo:
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(收稿日期:2019- 07- 30)
(本文编辑:边 佶)
更新日期/Last Update:
2020-05-22