[1]瞿小锋,李沛城,范伟健,等.机械取栓治疗心源性和非心源性急性脑卒中有效性和安全性对比分析[J].介入放射学杂志,2019,28(08):721-725.
 QU Xiaofeng,LI Peicheng,FAN Weijian,et al.Effectiveness and safety of mechanical thrombectomy for the treatment of stroke: comparative study between acute cardioembolic stroke and acute non- cardioembolic stroke[J].journal interventional radiology,2019,28(08):721-725.
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机械取栓治疗心源性和非心源性急性脑卒中有效性和安全性对比分析()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
28
期数:
2019年08期
页码:
721-725
栏目:
神经介入
出版日期:
2019-08-25

文章信息/Info

Title:
Effectiveness and safety of mechanical thrombectomy for the treatment of stroke: comparative study between acute cardioembolic stroke and acute non- cardioembolic stroke
作者:
瞿小锋 李沛城 范伟健 邓小文 李 波 刘一之
Author(s):
QU Xiaofeng LI Peicheng FAN Weijian DENG Xiaowen LI Bo LIU Yizhi.
Department of Interventional Radiology, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province 215006, China
关键词:
【关键词】 急性脑卒中 心源性栓塞 非心源性栓塞 机械取栓
文献标志码:
A
摘要:
【摘要】 目的 对比分析血管内机械取栓治疗心源性(CE)和非心源性(NCE)急性脑卒中的临床效果和安全性。 方法 回顾性分析2017年3月至2018年5月采用血管内机械取栓治疗的28例急性前循环缺血性脑卒中患者临床资料。根据TOAST研究组病因分型分为CE组(n=10例)和NCE组(n=18),比较两组患者血管再通率、补救性支架植入率、不良事件发生率、90 d内病死率、术前和术后7 d美国国立卫生研究院卒中量表(NIHSS)评分、术后90 d改良Rankin 量表(mRS)评分(mRS≤2分为预后良好)。 结果 CE组10例(100%)、NCE组17例(94.4%)患者达到血管良好再通[脑梗死溶栓(TICI)治疗后血流分级2b~3级],差异无统计学意义(P>0.05)。CE组术前、术后7 d NIHSS评分分别为15.88±3.40、7.75±4.03,NCE组分别为12.57±4.05、7.50±5.87,两组术后7 d NIHSS评分均较术前降低,差异有统计学意义(P<0.05)。CE组、NCE组分别植入0枚(0%)、6枚(33.3%)支架,差异有统计学意义(P<0.05)。CE组发生脑出血3例,NCE组发生脑出血2例,消化道出血1例,急性心力衰竭1例,两组不良事件发生率分别为30%、22.2%,差异无统计学意义(P>0.05)。CE组、NCE组术后90 d预后良好率分别为60%(6/10)、50%(9/18),差异无统计学意义(P>0.05);90 d 内病死率分别为20%(2/10)和22.2%(4/18),差异无统计学意义(P>0.05)。 结论 血管内机械性取栓治疗CE急性前循环缺血性脑卒中患者不增加术后不良事件和死亡发生率,可达到与NCE患者相似的临床效果。

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备注/Memo

备注/Memo:
(收稿日期:2018-09-18)
(本文编辑:边 佶)
更新日期/Last Update: 2019-08-21