[1]陈付文,刘金朝,康孝理,等.Solumbra技术在急性大动脉闭塞性脑梗死机械取栓中的初步应用观察 [J].介入放射学杂志,2019,28(06):515-520.
CHEN Fuwen,LIU Jinchao,KANG Xiaoli,et al.Preliminary application of Solumbra technique in mechanical thrombectomy in patients with acute large cerebral artery occlusion stroke[J].journal interventional radiology,2019,28(06):515-520.
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Solumbra技术在急性大动脉闭塞性脑梗死机械取栓中的初步应用观察
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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28
- 期数:
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2019年06期
- 页码:
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515-520
- 栏目:
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神经介入
- 出版日期:
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2019-06-25
文章信息/Info
- Title:
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Preliminary application of Solumbra technique in mechanical thrombectomy in patients with acute large cerebral artery occlusion stroke
- 作者:
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陈付文; 刘金朝; 康孝理; 赵玉铁; 杨思福; 李红伟; 史宏生; 汪子文
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- Author(s):
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CHEN Fuwen; LIU Jinchao; KANG Xiaoli; ZHAO Yutie; YANG Sifu; LI Hongwei; SHI Hongsheng; WANG Ziwen.
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Department of Interventional Radiology, Puyang Oilfield General Hospital, Puyang, Henan Province 457001, China
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- 关键词:
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【关键词】 Solumbra技术; 急性大动脉闭塞性脑梗死; 机械取栓; 支架; 抽吸
- 文献标志码:
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A
- 摘要:
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【摘要】 目的 探讨Solumbra技术在急性大动脉闭塞性脑梗死机械取栓治疗中应用的可行性、有效性、安全性和技术优势。方法 回顾性分析2016年1月至2017年12月采用血管内机械取栓治疗的59例急性大动脉闭塞性脑梗死患者临床资料。其中接受中间导管联合支架取栓患者31例(Solumbra组),接受常规导引导管联合支架取栓患者28例(常规支架取栓组)。比较两组患者手术相关指标、并发症及临床结果,分析Solumbra技术优势。结果 Solumbra组、常规支架取栓组患者间性别、年龄、术前美国国立卫生研究院卒中量表(NIHSS)评分、发病至动脉穿刺时间(OPT)、侧支循环评分差异均无统计学意义(P>0.05);颈内动脉(ICA)闭塞患者(12/31对2/28, χ2=8.100,P=0.004)、伴心房颤动患者(15/31对6/28, χ2=4.66,P=0.031)差异有显著统计学意义;血管最终成功再通达到改良脑梗死溶栓(mTICI)治疗后血流评分标准2b/3级比例分别为93.5%、85.7%,一次取栓再通率达mTICI 评分标准2b/3级比例分别为45.2%、25%,差异均无统计学意义(P>0.05);取栓次数[2(1,2)对2(1.25,3),Z=-2.177,P=0.029]、二次栓塞率(23.8%对39.3%, χ2=3.991,P=0.046)、穿刺至再灌注时间(PRT)[(81±31) min对(100±35) min,t=2.315,P=0.028]差异均有统计学意义;颅内出血发生率分别为19.4%、10.7%(P>0.05),90 d良好预后率[改良Rankin 量表(mRS)评分≤2]分别为48.4%、46.4%(P>0.05)。Solumbra组、常规支架取栓组ICA闭塞患者血管最终再通率分别为83.3%、0%(χ2=5.833,P=0.016);90 d良好预后率分别为41.6%、0%(P>0.05),但Solumbra组占优。结论 Solumbra技术是一种治疗急性大动脉闭塞性脑梗死的安全有效方法,与传统支架取栓术相比取栓效率更高,推荐用于一些路径血管迂曲、血栓负荷量大的患者。
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备注/Memo
- 备注/Memo:
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(收稿日期:2018-07-16)
(本文编辑:边 佶)
更新日期/Last Update:
2019-06-11