[1]范宏杰,寸江平,陆 阳,等.高强度聚焦超声消融多发性子宫肌瘤的影响因素[J].介入放射学杂志,2018,27(10):941-944.
　FAN Hongjie,CUN Jiangping,LU Yang,et al.Factors affecting the efficacy of high- intensity focused ultrasound ablation for multiple uterine fibroids[J].journal interventional radiology,2018,27(10):941-944.
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高强度聚焦超声消融多发性子宫肌瘤的影响因素()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年10期
页码:
941-944
栏目:
非血管介入
出版日期:
2018-10-25

文章信息/Info

Title:
Factors affecting the efficacy of high- intensity focused ultrasound ablation for multiple uterine fibroids
作者:
范宏杰;  寸江平;  陆 阳;  姚瑞红;  黄建强;  赵 卫
Author(s):
FAN Hongjie;  CUN Jiangping;  LU Yang;  YAO Ruihong;  HUANG Jianqiang;  ZHAO Wei.
Department of Medical Imaging， First Affiliated Hospital of Kunming Medical University， Kunming， Yunnan Province 650032， China
关键词:
【关键词】 高强度聚焦超声;  多发性子宫肌瘤;  能效因子;  消融率
文献标志码:
A
摘要:
【摘要】 目的 探讨高强度聚焦超声（HIFU）消融多发性子宫肌瘤的影响因素。方法 对HIFU治疗的139例多发性、症状性子宫肌瘤患者进行回顾性分析。将所有的子宫肌瘤分组，多分类变量分别设定哑变量后，将各个哑变量、患者年龄、均匀与否、肌瘤体积、T1增强信号、靶皮距、后声场距离设为自变量，将设能效因子（EEF）为因变量，用stepwise的方法进行多重线性回归分析。结果 患者平均年龄为（39.2±5.7）岁，平均肌瘤体积为（81.7±60.5） cm3，平均消融率为（73.9±14.2）%，平均EEF为（6.9±4.2） j/mm3。共6个自变量被选入多重线性回归模型，选择模型6进行分析（调整 R2=0.326，F=11.383，P＜0.001）。根据多重线性回归方程及其偏回归系数可知，EEF与位置、T1增强、肌瘤径线、肌瘤类型、后声场距离有线性相关关系，且T1增强对EEF影响最大。结论 HIFU对多发性子宫肌瘤的消融效果受肌瘤位置、血供、大小等因素的影响，其中血供（T1增强）对其影响较大。

参考文献/References:

［1］ 姜 曼， 赵 卫， 易根发， 等． 子宫肌瘤MRI特征与高强度聚焦超声消融疗效［J］． 介入放射学杂志， 2014， 23： 314- 319．
［2］ Peng S， Zhang L， Hu L， et al. Factors influencing the dosimetry for high- intensity focused ultrasound ablation of uterine fibroids： a retrospective study［J］. Medicine（Baltimore）， 2015， 94： e650.
［3］ Gong C， Yang B， Shi Y， et al. Factors influencing the ablative efficiency of high intensity focused ultrasound（HIFU） treatment for adenomyosis： a retrospective study［J］. Int J Hyperthermia， 2016， 32： 496- 503.
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［6］ Funaki K， Sawada K， Maeda F， et al. Subjective effect of magnetic resonance- guided focused ultrasound surgery for uterine fibroids［J］. J Obstet Gynaecol Res， 2007， 33： 834- 839.
［7］ Funaki K， Fukunishi H， Funaki T， et al. Magnetic resonance- guided focused ultrasound surgery for uterine fibroids： relationship between the therapeutic effects and signal intensity of preexisting T2- weighted magnetic resonance images［J］. Am J Obstet Gynecol， 2007， 196： 184.e1- 184.e6.
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备注/Memo

备注/Memo:
（收稿日期：２０１8-０3-０2）
（本文编辑：俞瑞纲）
更新日期/Last Update: 2018-10-15