[1]杨 伟,刘宗军,郜俊清,等.慢性重度心力衰竭伴窄QRS波患者去肾交感神经术1年疗效 [J].介入放射学杂志,2018,27(06):500-503.
 YANG Wei,LIU Zongjun,GAO Junqing,et al.Renal sympathetic denervation for patients with chronic severe heart failure and concomitant narrow QRS complex: observation of one- year curative effect[J].journal interventional radiology,2018,27(06):500-503.
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慢性重度心力衰竭伴窄QRS波患者去肾交感神经术1年疗效
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年06期
页码:
500-503
栏目:
心脏介入
出版日期:
2018-06-25

文章信息/Info

Title:
Renal sympathetic denervation for patients with chronic severe heart failure and concomitant narrow QRS complex: observation of one- year curative effect
作者:
杨 伟 刘宗军 郜俊清 金惠根 徐佑龙 徐三彬 刘伟伟
Author(s):
YANG Wei LIU Zongjun GAO Junqing JIN Huigen XU Youlong XU Sanbin LIU Weiwei
Department of Cardiology, Affiliated Putuo Hospital of Shanghai University of Traditional Chinese Medicine, Shanghai Municipal Putuo District Central Hospital, Shanghai 200062, China
关键词:
【关键词】 肾去神经化 心力衰竭 窄QRS波群 恶性心律失常 心功能
文献标志码:
A
摘要:
【摘要】 目的 探讨去肾交感神经术(RDN)对慢性重度心力衰竭(心衰)伴窄QRS波并植入埋藏式心脏复律除颤器(ICD)患者心功能和恶性心律失常的改善作用。方法 20例心电图QRS波<0.12 s、左心室射血分数(LVEF)<40%的慢性心衰患者,随机分为ICD植入后行RDN术组(甲组,10例)、ICD植入后未行RDN术组(乙组,10例)。记录随访期各例美国纽约心脏病协会(NYHA)心功能分级、血生化测定、超声心动图指标、6 min步行试验(6MWT)及ICD放电次数。结果 平均随访1.86年。随访期甲组较乙组NYHA心功能分级显著降低(1.50±0.53比3.20±0.79,P<0.001),6MWT步行距离显著增大[(450.50±25.57) m比(120.60±13.24) m,P<0.001],血清脑钠肽(BNP)水平降低[(167.36±128.49) pg/mL比(2 232.29± 2 451.64) pg/mL,P=0.016],左心室收缩末期内径缩小[(46.90±11.06) mm比(56.10±6.33) mm,P=0.035],LVEF增高[(39.50±9.63)%比(31.20±4.52)%,P=0.024]。随访末期甲组总ICD放电次数显著低于乙组(2次比40次,P<0.01);甲组RDN术后总放电次数显著低于术前(2次比31次,P<0.01)。结论 RDN术能有效改善慢性重度心衰伴窄QRS波患者长期心功能,提高运动耐量,减少ICD放电。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2017-11-02)
(本文编辑:边 佶)
更新日期/Last Update: 2018-06-09