[1]刘晶晶,吴志远,黄 蔚,等.CT引导下肺部肿瘤同轴穿刺活检联合微波消融治疗的临床应用 [J].介入放射学杂志,2018,27(02):141-146.
 LIU Jingjing,WU Zhiyuan,HUANG Wei,et al.The clinical application of CT- guided percutaneous coaxial needle biopsy combined with microwave ablation for lung tumors[J].journal interventional radiology,2018,27(02):141-146.
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CT引导下肺部肿瘤同轴穿刺活检联合微波消融治疗的临床应用


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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年02期
页码:
141-146
栏目:
非血管介入
出版日期:
2018-02-25

文章信息/Info

Title:
The clinical application of CT- guided percutaneous coaxial needle biopsy combined with microwave ablation for lung tumors
作者:
刘晶晶 吴志远 黄 蔚 丁晓毅 王忠敏
Author(s):
LIU Jingjing WU Zhiyuan HUANG Wei DING Xiaoyi WANG Zhongmin
Department of Interventional Radiology, Affiliated Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
关键词:
【关键词】 肺部肿瘤 CT引导 同轴穿刺 微波消融
文献标志码:
A
摘要:
【摘要】 目的 通过CT引导下行同轴穿刺活检联合微波消融(MWA)治疗肺部肿瘤的效果,探讨其技术特点、安全性、疗效及临床应用价值。方法 收集2014年8月至2016年6月上海瑞金医院放射介入科收治的肺部肿瘤患者20例,共23个肿瘤接受CT引导下同轴穿刺活检联合MWA治疗(其中肺部原发性肿瘤9例,转移瘤11例),根据肿瘤大小和形状,设置相应的消融功率和时间。术后随访4~26个月,通过定期复查胸部增强CT以观察其治疗效果。结果 行同轴穿刺活检病灶23个,肿瘤直径为0.80~2.40 cm,平均1.39 cm,行MWA病灶共23个,消融后即刻CT表现为病灶密度减低,穿刺活检阳性率为83.3%。20例患者完全缓解15例,部分缓解2例,无变化1例,进展2例,治疗有效率85%。术后1例发生气胸,1例发生血气胸,1例出现急性渗出性胸膜炎,2例发热,无一例发生针道转移,无一例因MWA治疗导致死亡。随访至2016年10月,17例患者存活,3例转移性肺癌患者均死于原发肿瘤进展(分别为肠癌、食管癌及肝癌)。1年局部控制率为65%,中位无进展生存时间为15.5个月(95%CI 16.6~23.4),1、2年生存率分别为90%、85%。结论 通过CT引导对肺部肿瘤行同轴穿刺活检联合MWA具有创伤小、活检阳性率高、安全性高、疗效好等特点,可以提高患者的生活质量并延长生存时间,是目前应用前景较好的介入治疗方式之一。

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备注/Memo

备注/Memo:
(收稿日期:2017-02-07)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2018-02-24