[1]赵 亮,曾 帅,马 鋆,等.彩色编码数字减影血管造影在定量分析化疗栓塞前后肝脏肿瘤灌注减少中的应用价值 [J].介入放射学杂志,2017,(04):313-317.
 ZHAO Liang,ZENG Shuai,MA Jun,et al.Application of color- coded DSA in quantitatively analyzing perfusion decrease of hepatic tumors before and after TACE[J].journal interventional radiology,2017,(04):313-317.
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彩色编码数字减影血管造影在定量分析化疗栓塞前后肝脏肿瘤灌注减少中的应用价值



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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2017年04期
页码:
313-317
栏目:
血管介入
出版日期:
2017-04-25

文章信息/Info

Title:
Application of color- coded DSA in quantitatively analyzing perfusion decrease of hepatic tumors before and after TACE
作者:
赵 亮 曾 帅 马 鋆 管 逊 郭哲中 王 嵇
Author(s):
ZHAO Liang ZENG Shuai MA Jun GUAN Xun GUO Zhezhong WANG Ji
Department of Radiology, Affiliated Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200127, China
关键词:
【关键词】 肝肿瘤灌注 肝动脉 肝动脉化疗栓塞 彩色数字减影血管造影 灌注减少
文献标志码:
A
摘要:
【摘要】 目的 探究彩色编码数字减影血管造影(ccDSA)在TACE术中对肝肿瘤灌注的即刻变化进行定量评测。方法 回顾性研究了35例TACE治疗肝细胞癌病例。TACE术前后用相同参数采集二维数字减影血管造影(2D- DSA)。图像序列均经二维ccDSA(2D- ccDSA)进行后处理。在ccDSA图像上测量感兴趣区域(ROI),得到时间密度曲线(time- contrast- intensity CI[t]),并获取肿瘤血供时间(TBST),曲线下面积(AUC)、最大强化值(CI- Peak)和最大上升斜率(MS)这些灌注参数来分析评估TACE前后顺行血流和肿瘤染色减少的程度。并对上述参数与主观血管造影栓塞终点(SACE)标准和临床结果之间的关系进行分析。结果 TACE前后灌注参数的比较有显著差异。AUC和CI- Peak在TACE术后大幅下降。TBST在术后较之术前有显著延迟。灌注减少30%~40%相当于SACE Ⅲ级,灌注减少 60%~70%相当于 SACE Ⅳ级。结论 2D- ccDSA可以客观地量化评估TACE术对肝肿瘤血流灌注的影响,为TACE术提供了定量评价动脉血流停滞程度和肿瘤染色减少的指标。

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备注/Memo

备注/Memo:
(收稿日期:2016-06-29)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2017-04-11