[1]侯明明,胡继红,赵 卫,等.经皮射频消融治疗门静脉高压性脾功能亢进的临床研究[J].介入放射学杂志,2014,(10):889-892.
 HOU Ming ming,HU Ji hong,ZHAO Wei,et al.Percutaneous radiofrequency ablation for the treatment of hypersplenism due to portal hypertension: a clinical study[J].journal interventional radiology,2014,(10):889-892.
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经皮射频消融治疗门静脉高压性脾功能亢进的临床研究 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年10期
页码:
889-892
栏目:
非血管介入
出版日期:
2014-10-25

文章信息/Info

Title:
Percutaneous radiofrequency ablation for the treatment of hypersplenism due to portal hypertension: a clinical study
作者:
侯明明 胡继红 赵 卫 易根发 王 滔
Author(s):
HOU Ming ming HU Ji hong ZHAO Wei YI Gen fa WANG Tao.
Department of Radiology, the First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province 650032, China
关键词:
【关键词】 射频消融 多极电极 B超/CT引导 脾功能亢进
文献标志码:
A
摘要:
【摘要】 目的 探讨B型超声/CT导引下经皮穿刺多极电极射频消融(RFA)治疗肝硬化门脉高压性脾功能亢进症(脾亢)的可行性、疗效和临床应用前景。方法 对28例门静脉高压性脾亢患者进行经皮RFA治疗。检测并比较患者术前以及术后2 d,2周以及1、3、6、10个月各时间点血常规、肝功能、凝血酶原时间;于术后即刻、1周,和1、3、10个月复查增强CT,采用CT后处理软件计算消融灶体积。结果 平均手术时间为(3.8 ± 1.1)h,平均消融时间为(2.7 ± 0.8)h;RFA毁损范围占脾脏总体积20% ~ 80%,平均为(50.5 ± 10.3)%;术后2 d外周血小板计数较术前明显下降[(19.5 ± 12.1) × 109/L],白细胞计数达到最高峰[(5.4 ± 0.2) × 109/L];术后2周直至随访10个月时白细胞和血小板计数、 肝功能以及凝血功能均较术前显著改善,差异有统计学意义(P < 0.05), 并发生硬化肝脏增生的现象,所有病例Child Pugh评分均为A级。仅1例大量腹水的Child Pugh C级患者术后出现腹胀和血性腹水,无其他严重并发症。结论 经皮B型超声/CT导向下RFA治疗门静脉高压性脾功能亢进是一种安全、有效的微创方法。

参考文献/References:

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备注/Memo

备注/Memo:
(收稿日期:2014-03-19)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2014-10-22