[1]王 娟,孙美玲,张宏涛,等.外放疗后复发颈部淋巴结转移癌17例125I粒子植入治疗的初步疗效[J].介入放射学杂志,2014,(09):784-787.
WANG Juan,SUN Mei ling,ZHANG Hong tao,et al.Radioactive 125I seed implantation for the treatment of recurrent cervical lymphatic metastases after radiotherapy: preliminary results in 17 cases[J].journal interventional radiology,2014,(09):784-787.
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外放疗后复发颈部淋巴结转移癌17例125I粒子植入治疗的初步疗效 ()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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- 期数:
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2014年09期
- 页码:
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784-787
- 栏目:
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非血管介入
- 出版日期:
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2014-09-25
文章信息/Info
- Title:
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Radioactive 125I seed implantation for the treatment of recurrent cervical lymphatic metastases after radiotherapy: preliminary results in 17 cases
- 作者:
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王 娟; 孙美玲; 张宏涛; 唐富龙; 隋爱霞; 夏海水
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- Author(s):
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WANG Juan; SUN Mei ling; ZHANG Hong tao; TANG Fu long; SUI Ai xia; XIA Hai shui.
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Department of Oncology, Hebei Provincial People’s Hospital, Shijiazhuang, Hebei Province 050051, China
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- 关键词:
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【关键词】 颈部淋巴结; 转移癌; 肿瘤复发; 125I粒子植入; 近距离放射治疗
- 文献标志码:
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A
- 摘要:
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【摘要】 目的 初步探讨125I粒子植入治疗外放后复发的颈部淋巴结转移癌的安全性及疗效。方法对2011年8月—2012年7月收治的17例颈部淋巴结转移癌既往接受外放疗再次复发患者行回顾性研究。17例患者23处病灶,应用近距离治疗计划系统(TPS)制订治疗计划,确定粒子数目、活度及分布,粒子活度0.3 ~ 0.8 mCi,肿瘤处方剂量为60 ~ 120 Gy,CT及B超双引导下植入,术后24 h内CT扫描,剂量验证D90为(81.4 ± 2.1)Gy。术后每2个月复查CT检测肿瘤大小变化并观察并发症。结果 随访6个月,局部控制率为65.2%,其中,小于4 cm的淋巴结控制率(CR + PR)为90%,而大于4 cm的为46%,P = 0.038,差异有统计学意义;颈Ⅰ、Ⅱ、Ⅲ、Ⅴ区淋巴结各控制率(CR + PR)与未控制率(SD + PD)比较, 差异无统计学意义(P > 0.05);孤立而边界清楚的21个淋巴结控制率为71%,融合而边界不清的淋巴结局部控制率为0。急性皮肤放疗反应Ⅱ度8例,Ⅰ度7例,无严重的其他放疗并发症。结论 125Ⅰ粒子植入治疗外放疗后复发的颈部淋巴结转移癌近期疗效好、创伤小、并发症少。小于4 cm且孤立、边界清楚的淋巴结更适合粒子植入治疗。
参考文献/References:
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备注/Memo
- 备注/Memo:
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(收稿日期:2013-12-25)
(本文编辑:俞瑞纲)
更新日期/Last Update:
2014-09-18