[1]吴 弘,王启平,秦永文,等. 经皮腔内室间隔心肌消融术治疗肥厚型梗阻性心肌病的长期疗效及安全性观察[J].介入放射学杂志,2014,(02):104-107.
 WU Hong,WANG Qi? ping,QIN Yong? wen,et al. Percutaneous transluminal septal myocardial ablation for hypertrophic obstructive cardiomyopathy: its long?蛳 term efficacy and safety[J].journal interventional radiology,2014,(02):104-107.
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 经皮腔内室间隔心肌消融术治疗肥厚型梗阻性心肌病的长期疗效及安全性观察 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2014年02期
页码:
104-107
栏目:
心脏介入
出版日期:
2014-02-28

文章信息/Info

Title:
 Percutaneous transluminal septal myocardial ablation for hypertrophic obstructive cardiomyopathy: its long?蛳 term efficacy and safety
作者:
 吴 弘 王启平 秦永文 赵仙先 郑 兴 徐荣良 马丽萍 陈少萍 朱嘉琦 郭志福 张 峥 李松华
Author(s):
 WU Hong WANG Qi?蛳 ping QIN Yong?蛳 wen ZHAO Xian?蛳 xian ZHENG Xing XU Rong?蛳 liang MA Li?蛳 ping CHEN Shao?蛳 ping ZHU Jia?蛳 qi GUO Zhi?蛳 fu ZHANG Zheng LI Song?蛳 hua.
 Department of Cardiology, Changhai Hospital, Second Military University, Shanghai 200433, China
关键词:
 【关键词】 肥厚型心肌病 导管消融 疗效 并发症随访
文献标志码:
A
摘要:
 【摘要】 目的 评价应用经皮腔内室间隔心肌消融术(percutaneous transluminal septal myocardial ablation,PTSMA)治疗肥厚型梗阻性心肌病(hypertrophic obstructive cardiomyopathy,HOCM)的长期疗效和安全性。方法 2003年1月—2012年3月对41例HOCM患者行PTSMA治疗,术后随访临床症状,评价活动耐量,超声评价心脏形态学。结果 术前超声测定患者室间隔厚度为(22.2 ± 4.1)mm,压力阶差为(99.2 ± 38.3)mmHg,左心导管检查测定压力阶差为(85.0 ± 27.9)mmHg,无水乙醇注射量平均为(2.3 ± 0.7) ml,分别消融1 ~ 2支前间隔支血管,第1间隔支消融32例,消融第2间隔支7例,消融第1和第2间隔支2例,术后即刻导管测左室流出道压差为(27.5 ± 19.4)mmHg,超声测定压力阶差为(39.0 ± 19.8)mmHg,与术前相比差异有统计学意义(P < 0.01),消融后室间隔厚度与术前相比差异无统计学意义(P > 0.05)。术后5例患者发生完全性房室传导阻滞,4例于1周内恢复,1例1周后未恢复,行永久性人工心脏起搏器植入术。患者无围术期死亡,随访1 ~ 9年,6例失访,32例患者术后临床症状较术前持续改善。1年随访室间隔厚度为(21.6 ± 3.4)mm,左室流出道压力阶差为(36.7 ± 17.6)mmHg,与术后(39.0 ± 19.8) mmHg相比,差异无统计学意义(P > 0.05)。3例患者随访期间症状复发,其中2例患者转外科行室间隔肌肉切除术,术后症状明显缓解,随访过程中无死亡病例,无缓慢性心律失常及恶性心律失常发生。结论 PTSMA能有效降低HOCM患者左室流出道压力阶差,改善活动耐量,安全性好,长期疗效满意。

参考文献/References:

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备注/Memo

备注/Memo:
 (收稿日期:2013-08-10)
更新日期/Last Update: