[1]高 峰,黄祥忠,任冬青,等.经动脉灌注化疗联合不同化疗方法治疗进展期胃癌60例对照研究[J].介入放射学杂志,2013,(10):857-859.
 GAO Feng,HUANG Xiang? zhong,REN Dong? qing,et al. Combination of chemotherapy and interventional management for the treatment of advanced gastric cancer: comparison study of different chemotherapy routes[J].journal interventional radiology,2013,(10):857-859.
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经动脉灌注化疗联合不同化疗方法治疗进展期胃癌60例对照研究 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年10期
页码:
857-859
栏目:
临床研究
出版日期:
2013-10-15

文章信息/Info

Title:
 Combination of chemotherapy and interventional management for the treatment of advanced gastric cancer: comparison study of different chemotherapy routes
作者:
 高 峰 黄祥忠 任冬青 沈 炜 郭新春 包凯沪
Author(s):
 GAO Feng HUANG Xiang?蛳 zhong REN Dong?蛳 qing SHEN Wei GUO Xin?蛳 chun BAO Kai?蛳 hu.
 Department of Interventional Therapy, Affiliated Jiangyin Hospital, Medical College of Dongnan University, Jiangyin, Jiangsu Province 214400, China
关键词:
 【关键词】 进展期胃癌 静脉化疗 口服化疗 介入
文献标志码:
A
摘要:
 【摘要】 目的 探讨不同化疗途径联合介入治疗进展期胃癌的安全性和疗效。方法 经胃镜检查及活组织病理学检查确诊的胃腺癌患者60例,随机分为A组和B组,每组30例。介入术中采用EOF方案(5?蛳 Fu 500 mg/m2,奥沙利铂130 mg/m2,表柔比星40 ~ 60 mg),A组在介入术后d 1 ~ 4经静脉使用CF(亚叶酸钙)150 mg/m2维持2 h,30 min后使用5?蛳 Fu 500 mg/m2 维持6 h,4周为1周期,B组术后口服替吉奥,40 ~ 60 mg,2次/d,d 8 ~ 21,休息1周,再进行下一周期的治疗。比较两组治疗后不良反应及生存率。结果 所有患者均完成至少2周期治疗。两组白细胞、血小板减少和恶心呕吐等不良反应比较差异有统计学意义(P < 0.05),两组K?蛳 M生存曲线比较差异无统计学意义(P = 0.625)。结论 替吉奥口服化疗较之5?蛳 Fu全身静脉化疗联合介入治疗进展期胃癌安全性更高,从而提高了患者的生活质量。

参考文献/References:

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备注/Memo

备注/Memo:
 (收稿日期:2013-05-17)
更新日期/Last Update: