[1]孙 鹏,隋守光,施洪峰,等.血管内支架成形术与尼莫地平在治疗血管性认知功能障碍的对比研究[J].介入放射学杂志,2013,(03):190-192.
 SUN Peng,SUI Shou? guang,SHI Hong? feng,et al.Endovascular stent angioplasty and orally administered nimodipine for vascular cognitive impairment: a comparative study[J].journal interventional radiology,2013,(03):190-192.
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血管内支架成形术与尼莫地平在治疗血管性认知功能障碍的对比研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2013年03期
页码:
190-192
栏目:
血管介入
出版日期:
2013-03-25

文章信息/Info

Title:
Endovascular stent angioplasty and orally administered nimodipine for vascular cognitive impairment: a comparative study
作者:
孙 鹏 隋守光 施洪峰 肖 颖 李海停 张晓飞 李 玮 王 宁
Author(s):
SUN Peng SUI Shou?蛳 guang SHI Hong?蛳 feng XIAO Ying LI Hai?蛳 ting ZHANG Xiao?蛳 fei LI Wei WANG Ning.
Department of Vascular and Neurological Intervention, the Affiliated Shengli Oil?蛳 field Central Hospital, Binzou Medical College, Dongying, Shandong Province 257000, China
关键词:
【关键词】 血管性认知功能障碍 支架成形术 尼莫地平 疗效
文献标志码:
A
摘要:
【摘要】 目的 初步评价血管内支架成形术与尼莫地平在治疗血管性认知功能障碍(vascular cognitive impairment,VCI)的疗效。方法 2009年6月至2011年6月诊断符合“第四届全国脑血管病会议”修订标准的VCI患者40例,经全脑血管造影术或头颈部CT血管成像确诊为脑供血动脉狭窄,并达到血管内治疗标准。将患者分为血管内支架成形术治疗组(支架组,20例)和口服尼莫地平治疗组(尼莫地平组,20例),接受治疗前行认知功能测定,用简易精神状态量表(MMSE)评分,并于治疗后6 h内和1、3、6个月分别行认知功能测定,观察各指标变化情况。结果 治疗前支架组与尼莫地平组比较,MMSE评分差异无统计学意义(P > 0.05)。治疗后1、3、6个月支架组MMSE评分较尼莫地平组显著升高,差异有统计学意义(P < 0.05)。支架组患者术后6 h内和1、3、6个月的MMSE评分与术前比较差异均有统计学意义(P < 0.05),而尼莫地平组仅在术后6个月的MMSE评分较术前差异有统计学意义(P < 0.05)。结论血管内支架成形术和口服尼莫地平治疗VCI均有效。血管内支架成形术后认知功能在短时间内得到改善,尼莫地平治疗则需较长时间才能改善。

参考文献/References:

[1] Derdeyn CP, Videen TO, Fritsch SM, et al. Compensatory mechanisms for chronic cerebral hypoperfusion in patients with carotid occlusion[J]. Stroke, 1999, 30: 1019 ?蛳 1024.[2] Mlekusch W, Mlekusch I, Haumer M, et al. Improvement of neurocognitive function after protected carotid artery stenting[J]. Catheter Cardiovasc Interv, 2008, 71: 114 ?蛳 119.[3] Rao R. The role of carotid stenosis in vascular cognitive impair?蛳 ment[J]. Eur Neurol, 2002, 203 ?蛳 204: 103 ?蛳 107.[4] Shibata M, Yamasaki N, Miyakawa T, et al. Selective impair?蛳 ment of working memory in a mouse model of chronic cerebral hypoperfusion[J]. Stroke, 2007, 38: 2826 ?蛳 2832.[5] Purandare N, Voshaar RC, Morris J, et al. Asymptomatic spontaneous cerebral emboli predict cognitive and functional decline in dementia[J]. Biol Psychiatry, 2007, 62: 339 ?蛳 344.[6] Rao R, Jackson S, Howard R. Neuropsychological impairment in stroke, carotid stenosis, and peripheral vascular disease[J]. Stroke, 1999, 30: 216 ?蛳 273.[7] Purandare N, Burns A, Daly KJ, et al. Cerebral emboli as a potential cause of Alzheimer’s disease and vascular dementia: case?蛳 control study[J]. BMJ, 2006, 332: 1119 ?蛳 1124.[8] Eliasziw M, Kennedy J, Hill MD, et al. Early risk of stroke after a transient ischemic attack in patients with internal carotid artery disease[J]. CMAJ, 2004, 170: 1105 ?蛳 1109.[9] 段 炜, 陈康宁, 柳春雨, 等. 解除颈动脉狭窄治疗轻度认知功能障碍的实验研究[J]. 国际脑血管病杂志, 2006, 14: 413 ?蛳 417.[10]杨 婷, 陈康宁. 颈动脉支架置入术改善患者认知功能障碍[J]. 现代生物医学进展杂志, 2008, l8: 2511 ?蛳 2513.[11] 王 炜, 王鲁宁. 尼莫地平对轻度认知功能损害患者的干预治疗研究[J]. 中华内科杂志, 2006, 45: 27 ?蛳 41.[12]李玥莹, 李群宝. 尼莫同治疗脑卒中后认知障碍疗效观察[J]. 新疆医科大学学报, 2009, 32: 987 ?蛳 988.

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备注/Memo

备注/Memo:
(收稿日期:2012-05-02)
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