[1]刘 影,张跃伟. 肝癌介入治疗用微粒型栓塞剂的研究进展[J].介入放射学杂志,2012,(11):969-972.
 LIU Ying,ZHANG Yue? wei.. Microparticle embolic agents used in interventional therapy for hepatocellular carcinomas: current progress in research[J].journal interventional radiology,2012,(11):969-972.
点击复制

 肝癌介入治疗用微粒型栓塞剂的研究进展 ()

PDF下载中关闭

分享到:

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年11期
页码:
969-972
栏目:
综述
出版日期:
2012-11-28

文章信息/Info

Title:
 Microparticle embolic agents used in interventional therapy for hepatocellular carcinomas: current progress in research
作者:
 刘 影 张跃伟
Author(s):
 LIU Ying ZHANG Yue?蛳 wei.
 Department of Interventional Radiology, the Affiliated Zhongshan Hospital of Dalian University, Dalian 116001, China
关键词:
 【关键词】 微粒型栓塞剂 肝癌 肝动脉化疗栓塞术
文献标志码:
A
摘要:
 【摘要】 近年来,多项临床随机对照研究表明与保守治疗相比经导管肝动脉化疗栓塞术(TACE)治疗中晚期肝癌(HCC)取得了良好的临床疗效。随着栓塞材料的发展,新型微粒栓塞剂因具有生物相容性、药物缓释作用等优点而成为临床研究的热点,有望进一步提升TACE治疗肝癌的临床疗效。目前国内外已有多种微粒型栓塞剂应用于临床,现将其生物特性及临床疗效做如下综述。

参考文献/References:

 [1] Ferlay J, Shin HR, Bray F, et al. Estimates of worldwide burden of Cancer in 2008: GLOBOCAN 2008[J]. Int J Cancer, 2010, 127: 2893 ?蛳 2917.
[2] Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma[J]. Lancet, 2012, 379: 1245 ?蛳 1255.
[3] Takayasu K, Arii S, Ikai I, et al. Overall survival after transarterial lipiodol infusion chemotherapy with or without embolization for unresectable hepatocellular carcinoma: propen?蛳sity score analysis[J]. Am J Roentgenol, 2010, 194: 830 ?蛳 837.
[4] Bonomo G, Pedicini V, Monfardini L, et al. Bland embolization in patients with unresectable hepatocellular carcinoma using precise, tightly size?蛳 calibrated, anti?蛳 inflammatory microparticles: first clinical experience and one?蛳 year follow?蛳 up[J]. Cardiovasc Intervent Radiol, 2010, 33: 552 ?蛳 559.
[5] Lammer J, Malagari K, Vogl T, et al. Prospective randomized study of doxorubicin?蛳 eluting?蛳 bead embolization in the treatment of hepatocellular carcinoma: results of the PRECISION V study[J]. Cardiovasc Intervent Radiol, 2010, 33: 41 ?蛳 52.
[6] Salem R, Lewandowski RJ, Kulik L, et al. Radioembolization results in longer time?蛳 to?蛳 progression and reduced toxicity compared with chemoembolization in patients with hepatocellular carcinoma[J]. Gastroenterology, 2011, 140: 497 ?蛳 507. e2.
[7] Yamasaki T, Hamabe S, Saeki I, et al. A novel transcatheter arterial infusion chemotherapy using iodized oil and degradable starch microspheres for hepatocellular carcinoma: a prospective randomized trial[J]. J Gastroenterol, 2011, 46: 359 ?蛳 366.
[8] 李裕波, 林进令, 刘志明. 白芨作为血管栓塞剂的应用[J]. 介入放射学杂志, 2010, 19: 835 ?蛳 838.
[9] Vogl TJ, Naguib NN, Nour?蛳 Eldin NE, et al. Review on transar?蛳 terial chemoembolization in hepatocellular carcinoma: palliative, combined, neoadjuvant, bridging, and symptomatic indications[J]. Eur J Radiol, 2009, 72: 505 ?蛳 516.
[10] Stampfl U, Stampfl S, Bellemann N, et al. Experimental liver embolization with four different spherical embolic materials:impact on inflammatory tissue and foreign body reaction[J]. Cardiovasc Interv Radiol, 2009, 32: 303 ?蛳 312.
[11] van Malenstein H, Maleux G, Vandecaveye V, et al. A random?蛳 ized phase Ⅱ study of drug?蛳 eluting beads versus transarterial chemoembolization for unresectable hepatocellular carcinoma[J]. Onkologie, 2011, 34: 368 ?蛳 376.
[12] Grosso M, Vignali C, Quaretti P, et al. Transarterial chemoem?蛳 bolization for hepatocellular carcinoma with drug?蛳 eluting microspheres: preliminary results from an Italian multicentre study[J]. Cardiovasc Intervent Radiol, 2008, 31: 1141 ?蛳 1149.
[13] Malagari K, Chatzimichael K, Alexopoulou E, et al. Transar?蛳 terial chemoembolization of unresectable hepatocellular carci?蛳 noma with drug eluting beads: results of an open?蛳 label study of 62 patients[J]. Cardiovasc Intervent Radiol, 2008, 31: 269 ?蛳 280.
[14] Varela M, Real MI, Burrel M, et al. Chemoembolization of hepatocellular carcinoma with drug eluting beads: efficacy and doxorubicin pharmacokinetics[J]. J Hepatol, 2007, 46: 474 ?蛳 481.
[15] Nosher JL, Ohman?蛳 Strickland PA, Jabbour S, et al. Changes in liver and spleen volumes and liver function after radioembolization with yttrium?蛳 90 resin microspheres[J]. J Vasc Interv Radiol, 2011, 22: 1706 ?蛳 1713.
[16] Purushotham S, Ramanujan RV. Thermoresponsive magnetic composite nanomaterials for multimodal Cancer therapy[J]. Acta Biomater, 2010, 6: 502 ?蛳 510.
[17] Sun JB, Duan JH, Dai SL, et al. In vitro and in vivo antitumor effects of doxorubicin loaded with bacterial magnetosomes (DBMs) on H22 cells: the magnetic bio?蛳 nanoparticles as drug carriers[J]. Cancer Lett, 2007, 258: 109 ?蛳 117.
[18] Tam KY, Leung KC, Wang YX. Chemoembolization agents for cancer treatment[J]. Eur J Pharm Sci, 2011, 44: 1 ?蛳 10.
[19] Marelli L, Stigliano R, Triantos C, et al. Transarterial therapy for hepatocellular carcinoma: which technique is more effective? A systematic review of cohort and randomized studies[J]. Cardiovasc Intervent Radiol, 2007, 30: 6 ?蛳 25.
[20] Burrel M, Reig M, Forner A, et al. Survival of patients with hepatocellular carcinoma treated by transarterial chemoembolisa?蛳 tion (TACE) using Drug Eluting Beads. Implications for clinical practice and trial design[J]. J Hepatol, 2012, 56: 1330 ?蛳 1335.
[21] Lance C, Mclennan G, Obuchowski N, et al. Comparative analysis of the safety and efficacy of transcatheter arterial chemoembolization and yttrium?蛳 90 radioembolization in patients with unresectable hepatocellular carcinoma[J]. J Vasc Interv Radiol, 2011, 22: 1697 ?蛳 1705.
[22] 姚雪松, 李 槐. 不可手术切除的肝细胞癌的疗效评价标准-改良RECIST标准更可靠[J]. 介入放射学杂志, 2012, 21: 177 ?蛳 179.

相似文献/References:

[1].Spontaneous regression of a giant basilar artery aneurysm in a young adult after surgical injury :case report and literature review[J].介入放射学杂志,2007,(10):718.
 ZHANG He,LI Ming-hua,WANG Chun,et al.Spontaneous regression of a giant basilar artery aneurysm in a young adult after surgical injury :case report and literature review[J].journal interventional radiology,2007,(11):718.
[2]李统怀,郑红枫. 子宫动脉栓塞治疗子宫瘢痕妊娠11例[J].介入放射学杂志,2011,(11):898.
 LI Tong-huai,ZHENG Hong-feng..Clinical application of uterine artery embolization in treating uterine scar pregnancy[J].journal interventional radiology,2011,(11):898.
[3]吕维富,张爱武,周春泽,等. 子宫动脉的三维DSA表现及其最佳显示体位探讨[J].介入放射学杂志,2011,(11):853.
 LV Wei-fu,ZHANG Ai-wu,ZHOU Chun-ze,et al.3D-DSA findings of uterine artery and its optimal projection position[J].journal interventional radiology,2011,(11):853.
[4]张 靖,周少毅,陈昆山,等.经导管动脉硬化栓塞联合注射硬化治疗婴儿颌面部巨大高流量血管瘤[J].介入放射学杂志,2011,(11):848.
 ZHANG Jing,ZHOU Shao-yi,CHEN Kun-shan,et al.Transcatheter arterial sclerosing embolization with injection sclerotherapy for the treatment of huge and high-flow maxillofacial hemangiomas in infants[J].journal interventional radiology,2011,(11):848.
[5]谢小西,吕银祥,章宏欣,等. 肝动脉化疗栓塞、射频消融联合125Ⅰ粒子植入 治疗原发性肝癌的临床应用[J].介入放射学杂志,2011,(11):863.
 XIE Xiao-xi,LV Yin-xiang,ZHANG Hong-xin,et al.The clinical application of TACE together with RFA and 125Ⅰ seed implantation in treating hepatocellular carcinoma[J].journal interventional radiology,2011,(11):863.
[6]王铭义,王 峰. 脑灌注成像在颈动脉狭窄介入治疗中的应用[J].介入放射学杂志,2011,(11):915.
 WANG Ming-yi,WANG Feng..Application of brain perfusion imaging in interventional treatment of carotid artery stenosis[J].journal interventional radiology,2011,(11):915.
[7]杜 猛,张锦生. 介入治疗急性深静脉血栓的临床观察[J].介入放射学杂志,2011,(11):858.
 DU Meng,ZHANG Jing-sheng..Interventional therapy for acute deep venous thrombosis: a clinical observation[J].journal interventional radiology,2011,(11):858.
[8]孟庆娜,李国庆,白晓冬. 急性心肌梗死介入治疗术中恶心呕吐的护理[J].介入放射学杂志,2011,(11):913.
 MENG Qing-na,LI Guo-qing,BAI Xiao-dong..The nursing care of nausea and vomiting occurred in interventional treatment for acute myocardial infarction[J].journal interventional radiology,2011,(11):913.
[9]王海亭,蒋忠仆,周 毅,等. 透视引导下鱼肝油酸钠泡沫硬化剂治疗下肢静脉曲张30例[J].介入放射学杂志,2011,(11):905.
 WANG Hai-ting,JIANG Zhong-pu,ZHOU Yi,et al.Fluoroscopically-guided foam sclerotherapy with sodium morrhuate for the treatment of lower extremity varices[J].journal interventional radiology,2011,(11):905.
[10]杜 鲲,管 生,胡小波,等. 原发性肝癌TACE术后完全缓解病灶磁共振 ADC值可重复性及一致性研究[J].介入放射学杂志,2011,(11):867.
 DU Kun,GUAN Sheng,HU Xiao-bo,et al.Magnetic resonance apparent diffusion coefficient values of the completely remitted lesions of primary hepatocellular carcinoma after TACE: a study of their repeatability and consistency[J].journal interventional radiology,2011,(11):867.

备注/Memo

备注/Memo:
 (收稿日期:2012-04-19)
更新日期/Last Update: