[1]帕哈尔丁·白克热,杨树法,黄伍奎,等.肝动脉化疗栓塞联合射频消融术治疗30例原发性大肝癌的疗效评价[J].介入放射学杂志,2012,(04):322-326.
 ,,et al.TACE combined with radiofrequency ablation for massive primary hepatocellular carcinomas: a clinical therapeutic evaluation [J].journal interventional radiology,2012,(04):322-326.
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肝动脉化疗栓塞联合射频消融术治疗30例原发性大肝癌的疗效评价 ()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2012年04期
页码:
322-326
栏目:
临床研究
出版日期:
2012-04-28

文章信息/Info

Title:
TACE combined with radiofrequency ablation for massive primary hepatocellular carcinomas: a clinical therapeutic evaluation  
作者:
 帕哈尔丁·白克热 杨树法 黄伍奎 王海林
Author(s):
 PAHAERDING Baikere YANG Shufa HUANG Wukui WANG Hailing.  
 Department of Interventional Radiology, the Affiliated Tumor Hospital of Xinjiang Medical University, Urmqi 830011, China
关键词:
 【关键词】 肝癌 介入治疗 肝动脉化疗栓塞 射频消融
文献标志码:
A
摘要:
 【摘要】 目的 探讨肝动脉化疗栓塞(TACE)联合射频消融(RFA)治疗原发性大肝癌(病灶平均长径7.9 cm)的疗效。 方法 自2009年8月至2010年9月,对在新疆医科大学附属肿瘤医院治疗的30例原发性肝细胞大肝癌的患者的41个病灶,先行TACE治疗2 ~ 3次,2 ~ 4周后行RFA 1 ~ 3次。术后随访临床症状、B超造影或CT扫描的肿瘤大小、肝功能、AFP以及生存期。结果 30例患者术后临床症状均较术前缓解。术后CT复查显示:18个(43.9%)肿瘤病灶完全坏死,内部及边缘无明显强化;23个(56.1%)肿瘤病灶部分坏死。AFP下降25例(83.3%)、不变2例(6.7%),升高3例(10.0%)。并发症中1例出现表皮灼伤,2例顽固性呃逆,3例肝内出血,1例肝脓肿,4例术后出现严重低蛋白血症。所有病例随访4.1 ~ 20.1个月,中位生存期为8.1个月,平均生存期11.1个月。结论 肝动脉化疗栓塞联合RFA是治疗不可切除的原发性大肝癌的有效方法,确切结论仍需要大样本的随机对照临床研究进一步证实。

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 (收稿日期:20110726)
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