[1]王福安,王立富,王书祥,等. 血管内化疗栓塞术联合椎体成形术治疗椎体转移性肿瘤的临床应用分析[J].介入放射学杂志,2011,(12):1003-1006.
　WANG Fu-an,WANG Li-fu,WANG Shu-xiang,et al.Intravascular chemoembolization combined with percutaneous vertebroplasty for the treatment of metastatic vertebral tumors: an analysis of its clinical application[J].journal interventional radiology,2011,(12):1003-1006.
点击复制

 血管内化疗栓塞术联合椎体成形术治疗椎体转移性肿瘤的临床应用分析 ()

PDF下载中关闭

分享到：

《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2011年12期
页码:
1003-1006
栏目:
临床研究
出版日期:
2011-12-30

文章信息/Info

Title:
Intravascular chemoembolization combined with percutaneous vertebroplasty for the treatment of metastatic vertebral tumors: an analysis of its clinical application
作者:
 王福安;  王立富;  王书祥;  孙 陵;  吕朋华;  黄文诺;  何仕诚;  滕皋军【
225001 扬州大学临床医学院介入科；南京东南大学附属中大医院
Author(s):
WANG Fu-an;  WANG Li-fu;  WANG Shu-xiang;  SUN Ling;  LV Peng-hua;  HUANG Wen-nuo;  HE Shi-cheng;  TENG Gao-jun.

Department of Interventional Radiology, Clinical Medical College of Yangzhou University, Yangzhou 225001, China
关键词:
 ; 【关键词】 椎体;  转移瘤;  椎体成形术;  化疗栓塞;  介入放射学
分类号:
R738.1
文献标志码:
A
摘要:
 摘要】 目的 探讨血管内化疗栓塞术和经皮椎体成形术（ＰＶＰ）联合治疗椎体转移性肿瘤的临床疗效。方法 采用血管内化疗栓塞术及ＰＶＰ联合治疗２５例（共３２节椎体）椎体转移性肿瘤患者，随访并分析其疼痛症状缓解情况。结果 所有患者均成功行椎体肿瘤供血动脉化疗栓塞术及ＰＶＰ，其中有１５例患者行碘化油 ＋ 吡柔比星乳剂化疗栓塞，所用碘化油平均１．８ ｍｌ［（１．４ ± １．０）ｍｌ］，吡柔比星１０ ｍｇ，其余１０例行吡柔比星１０ ｍｇ灌注化疗后采用明胶海绵颗粒栓塞。２５例患者行椎体肿瘤血管化疗栓塞后１周内２０例患者疼痛症状有所缓解（缓解率８０％），１周内所有患者均接受ＰＶＰ，手术均获得成功，其中８例患者各１节椎体行双侧穿刺，其余均为单侧穿刺，技术成功率１００％。１１节胸椎骨水泥平均注入量为（３．３ ± １．６）ｍｌ，２１节腰椎为（４．２ ± １．５）ｍｌ，术后平均生存时间（１０．０ ± ５．６）个月，ＰＶＰ术后２４ ｈ，１周及１、３、６和１２个月有效率分别为１００％（２５／２５）、９６％（２４／２５）、８４％（２１／２５）、８２．６％（１９／２３）、７８．９％（１５／１９）和６９．２％（９／１３）。结论 采用血管内化疗栓塞术和ＰＶＰ联合治疗椎体转移性肿瘤可迅速缓解椎体疼痛症状且持续时间较长，可明显提高患者的生活质量。

参考文献/References:

[1] Sciubba DM, Gokaslan ZL. Diagnosis and management of metastatic spine disease[J]. J Neurosurg Spine, 2006, 15: 141 - 151.
[2] Harel R, Angelov L. Spine metastases: current treatments and future directions[J]. Eur J Cancer, 2010, 46: 2696 - 2707.
[3] Sciubba DM, Gokaslan ZL. Diagnosis and management of metastatic spine disease[J]. Surg Oncol, 2006, 15: 141 - 151.
[4] 邓 钢, 何仕诚, 滕皋军, 等. 经皮椎体成形术治疗脊椎恶性肿瘤[J]. 介入放射学杂志, 2005, 14: 261 - 265.
[5] 高 鹏, 郭建波, 丛培生, 等. 经皮椎体成形术及血管内栓塞化疗治疗椎体转移瘤[J]. 大连医科大学学报, 2005, 27: 355 - 358.
[6] Chiras J, Cormier E, Baragan H, et al. Interventional radiology in bone metastases[J]. Bull Cancer, 2007, 94: 161 - 169.
[7] Mathis JM, Barr JD, Belkoff SM, et al. Percutaneous vertebro-plasty: a developing standard of care for vertebral compression fractures[J]. AJNR, 2001, 22: 373 - 381.
[8] 何仕诚, 滕皋军. 经皮椎体成形术[J]. 介入放射学杂志, 2001, 10: 56 - 58.
[9] Belkoff SM, Mathis JM, Jasper LE, et al. The biomechanics of vertebroplasty. The effect of cement volume on mechanical behavior[J]. Spine (Phila Pa 1976), 2001, 26: 1537 - 1541.

相似文献/References:

[1]张 琳,黄学全,王健,等.自主研发电化学治疗同轴电极与传统针式电极电解效应的对比研究[J].介入放射学杂志,2012,(02):148.
　ZHANG Lin,HUANG Xue-quan,WANG Jian,et al.The electrolytic effect in electrochemotherapy: a comparative study between self-prepared coaxial electrode and conventional needle electrode[J].journal interventional radiology,2012,(12):148.
[2]赵 玮,王伟中,陈莹,等.耳部动静脉畸形供血动脉的血管造影研究[J].介入放射学杂志,2012,(02):103.
　ZHAO Wei,WANG Wei-zhong,CHEN Ying,et al.Angiographic findings of the feeding arteries of auricular arteriovenous malformations[J].journal interventional radiology,2012,(12):103.
[3]邹俊民,龙世娟,张振明. 改良髂内动脉化疗联合放疗治疗Ⅲ~Ⅳa期 子宫颈癌32例[J].介入放射学杂志,2012,(02):123.
　ZOU Jun-min,LONG Shi-Juan,ZHANG Zheng-ming..Improved internal iliac artery chemotherapy combined with radiotherapy for the treatment of stage Ⅲ-Ⅳa cervical cancers[J].journal interventional radiology,2012,(12):123.
[4]王昌明,李 选,宋世兵,等.肝门部胆道引流管折叠技术在肝移植后胆道非吻合口狭窄治疗中的应用[J].介入放射学杂志,2012,(02):136.
　WANG Chang-ming,LI Xuan,SONG Shi-bing,et al.The application of biliary catheter folding technique in the treatment of hilar nonanastomotic biliary strictures after orthotopic liver transplantation[J].journal interventional radiology,2012,(12):136.
[5]赵玉峰,孙玉琴,韩晓静,等. 输卵管介入再通术后受孕时机的研究[J].介入放射学杂志,2012,(02):158.
　ZHAO Yu-feng,SUN Yu-qin,HAN Xiao-jing,et al.The optimal time for conception after fallopian tube recanalization therapy[J].journal interventional radiology,2012,(12):158.
[6]含 笑,曹建民,史东宏,等.吉西他滨、顺铂动静脉联合化疗治疗晚期非小细胞肺癌的近期疗效分析[J].介入放射学杂志,2012,(02):119.
　HAN Xiao,CAO Jian-min,SHI Dong-hong,et al.Bronchial artery infusion of Gemcitabine and Cisplatin combined with systemic chemotherapy for advanced non-small cell lung cancer: its short-term efficacy[J].journal interventional radiology,2012,(12):119.
[7]姚雪松,李 槐.不可手术切除的肝细胞癌的疗效评价标准——改良ＲＥＣＩＳＴ标准更可靠[J].介入放射学杂志,2012,(03):177.
　. Ｔｈｅｒａｐｅｕｔｉｃ ｅｖａｌｕａｔｉｏｎ ｃｒｉｔｅｒｉｏｎ ｏｆ ｉｎｏｐｅｒａｂｌｅ ｈｅｐａｔｏｃｅｌｌｕｌａｒ ｃａｒｃｉｎｏｍａｓ： ｍｏｄｉｆｉｅｄ ＲＥＣＩＳＴ ａｓ ａ ｍｏｒｅ ｒｅｌｉａｂｌｅ ｓｔａｎｄａｒｄ[J].journal interventional radiology,2012,(12):177.
[8]齐 立,李慎茂,俸军林,等. 动脉溶栓与机械碎栓联合动脉溶栓的对比分析[J].介入放射学杂志,2012,(03):180.
　,,et al. Ｃｏｍｐａｒｉｓｏｎ ｏｆ ｔｈｅ ｔｈｅｒａｐｅｕｔｉｃ ｅｆｆｉｃａｃｙ ｂｅｔｗｅｅｎ ｓｉｍｐｌｅ ａｒｔｅｒｉａｌ ｔｈｒｏｍｂｏｌｙｓｉｓ ａｎｄ ｍｅｃｈａｎｉｃａｌ ｔｈｒｏｍｂｅｃｔｏｍｙ ｃｏｍｂｉｎｅｄ ｗｉｔｈ ａｒｔｅｒｉａｌ ｔｈｒｏｍｂｏｌｙｓｉｓ ｆｏｒ ａｃｕｔｅ ｃｅｒｅｂｒａｌ ｉｎｆａｒｃｔｉｏｎ ａｔ ｉｔｓ ｕｌｔｒａｅａｒｌｙ ｓｔａｇｅ[J].journal interventional radiology,2012,(12):180.
[9]石 潆,赵 卫,沈 进,等.脑动静脉畸形栓塞治疗术并发颅内出血的原因及处理[J].介入放射学杂志,2012,(03):185.
　,,et al.Ｉｎｔｒａｃｒａｎｉａｌ ｈｅｍｏｒｒｈａｇｅ ｄｕｅ ｔｏ ｅｍｂｏｌｉｚａｔｉｏｎ ｔｈｅｒａｐｙ ｆｏｒ ｃｅｒｅｂｒａｌ ａｒｔｅｒｉｏｖｅｎｏｕｓ ｍａｌｆｏｒｍａｔｉｏｎ： ｉｔｓ ｃａｕｓｅｓ ａｎｄ ｍａｎａｇｅｍｅｎｔ [J].journal interventional radiology,2012,(12):185.
[10]周 慷,李晓光,金征宇,等.清宫术前子宫动脉化疗栓塞术治疗瘢痕妊娠的疗效分析[J].介入放射学杂志,2012,(03):190.
　,,et al.Ｔｈｅｒａｐｅｕｔｉｃ ａｎａｌｙｓｉｓ ｏｆ ｂｉｌａｔｅｒａｌ ｕｔｅｒｉｎｅ ａｒｔｅｒｙ ｃｈｅｍｏｅｍｂｏｌｉｚａｔｉｏｎ ｐｅｒｆｏｒｍｅｄ ｂｅｆｏｒｅ ｕｔｅｒｉｎｅ ｄｉｌａｔｉｏｎ ａｎｄ ｃｕｒｅｔｔａｇｅ ｆｏｒ ｃｅｓａｒｅａｎ ｓｃａｒ ｐｒｅｇｎａｎｃｙ [J].journal interventional radiology,2012,(12):190.

备注/Memo

备注/Memo:
(收稿日期:2011-03-21)
更新日期/Last Update: