[1]张琳,牟玮,王健,等.乙酸化学消融联合肝动脉化疗栓塞治疗肝脏恶性肿瘤[J].介入放射学杂志,2007,(12):831.
　ZHANG Lin,MU Wei,WANG Jian,et al.CT fluoroscopic guidance percutaneous acetic acid injection tumor ablation and TACE for the malignant liver tumor[J].journal interventional radiology,2007,(12):831.
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乙酸化学消融联合肝动脉化疗栓塞治疗肝脏恶性肿瘤()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2007年12期
页码:
831
栏目:
非血管介入
出版日期:
2007-12-15

文章信息/Info

Title:
CT fluoroscopic guidance percutaneous acetic acid injection tumor ablation and TACE for the malignant liver tumor
作者:
张琳; 牟玮; 王健; 等
400038  重庆  第三军医大学西南医院放射科 
Author(s):
ZHANG Lin; MU Wei; WANG Jian; ZHU Jie-hui; LIU Feng-xiu; HU Chun-fang; LI Zhong-hui; HUANG Xue-quan
Department of Radiology，Southwest Hospital，The Third Military Medical University，Chongqing４０００３８，China
关键词:
肝脏肿瘤; CT透视; 乙酸; 经动脉化疗栓塞; 消融
分类号:
R７３５.７
文献标志码:
A
摘要:
目的评价CT透视引导经皮穿刺乙酸注射（PAI）联合肝动脉化疗栓塞治疗肝脏恶性肿瘤的安全性和疗效。方法收集我院２００５年５月至２００７年６月在实时CT透视导向下PAI治疗肝动脉化疗栓塞术后复发肝脏恶性肿瘤７８例，其中肝细胞癌７０例、转移性腺癌８例。根据病灶大小每次注入５０％～６０％乙酸２～１０ml，乙酸内加入１ml对比剂混匀，以了解乙酸在肿块内的弥散程度和范围。注射后１周影像检查，根据情况重复注射１～２次。结果在实时CT透视下均能准确穿刺到靶点。注入后４２例出现轻中度疼痛，无其他并发症。全部病例均经CT随访，３个月时，其中瘤灶缩小３２例（４１％），肿瘤大小无变化３８例（４９％），肿瘤增大８例（１０％）。７８例３个月随访，全部生存；４８例随访１年，４０例生存，８例失访。结论CT透视引导下经皮乙酸消融联合肝动脉化疗栓塞治疗肝脏恶性肿瘤安全、有效。

参考文献/References:

［１］de Mey J，Op de Beeck B，Meysman M，et al．Real time CT-fluoroscopy：diagnostic and therapeutic applications［J］．Eur J Radiol，２０００，３４：３２-４０．
［２］张琳，黄学全，王健，等．螺旋CT透视下经皮穿刺活检在肺部小结节病变中的应用［J］．第三军医大学学报，２００２，２４：６６９-７０１．
［３］Kirchner J，Kickuth R，Laufer U，et al．CT fluoroscopy-assisted puncture of thoracic and abdominal masses：a randomized trial［J］．Clin Radiol，２００２，５７：１８８-１９２．
［４］Froelich JJ，Ishaque N，Regn J，et al．Guidance of percutaneous pulmonary biopsies with real-time CT fluoroscopy［J］．Eur J Radiol，２００２，４２：７４-７９．
［５］Kato R，Katada K，Anno H，et al．Radiation dosimetry at CT fluoroscopy：physician’s hand dose and development of needle holders［J］．Radiology，１９９６，２０１：５７６-５７８．
［６］Ohnishi K，Nomura F，Ito S，et al．Prognosis of small hepatocellar carcinoma less than３cm after percutaneous acetic acid injection study of９１cases［J］．Hepatology，１９９６，２３：９９４-１００２．
［７］Garcea G，Lloyd TD，Aylott C，et al．The emergent role of focal liver ablation techniques in the treatment of primary and secondary liver tumours［J］．Eur J Cancer，２００３，１-１５．

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备注/Memo

备注/Memo:
收稿日期：２００７-０８-２０
更新日期/Last Update: 2007-12-15