[1]吴志远,张华,吴达明,等.双侧岩下窦采样诊断ACTH依赖性库欣综合征的应用研究[J].介入放射学杂志,2010,(05):361.
WU Zhiyuan,ZHANG Hua,WU Daming,et al.The application of bilateral inferior petrosal sinus sampling in diagnosing ACTH-dependent Cushing's syndrome[J].journal interventional radiology,2010,(05):361.
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双侧岩下窦采样诊断ACTH依赖性库欣综合征的应用研究()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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- 期数:
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2010年05期
- 页码:
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361
- 栏目:
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血管介入
- 出版日期:
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2010-05-15
文章信息/Info
- Title:
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The application of bilateral inferior petrosal sinus sampling in diagnosing ACTH-dependent Cushing's syndrome
- 作者:
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吴志远; 张华; 吴达明; 等
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200025上海交通大学医学院附属瑞金医院放射科(吴志远、张华、吴达明、杨燕敏、顾俊玮、张伟华、陈克敏);内分泌科(苏廷为)
- Author(s):
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WU Zhi-yuan; ZHANG Hua; WU Da-ming; SU Ting-wei; YANG Yan-min; GU Jun-wei; ZHANG Wei-hua; CHEN Ke-min.
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the Affiliated Ruijin Hospital,School of Medicine,Shanghai Jiaotong University,Shanghai200025,China
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- 关键词:
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岩下窦采样; 库欣综合征; 库欣病; 诊断
- 分类号:
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R586.2
- 摘要:
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目的探讨双侧岩下窦采样(BIPSS)对ACTH依赖性库欣综合征(CS)的诊断价值。方法43例CS患者行BIPSS和垂体MRI 检查,用ROC曲线分析它们的诊断价值。结果BIPSS定性诊断CS的灵敏度为0.95、特异度为1.00、阳性预测值为1.00、阴性预测值为0.71,ROC曲线下面积(AUC)大于垂体MRI ;对库欣病(CD)垂体瘤的定位诊断准确率为84.21%,亦高于垂体MRI 。结论BIPSS是诊断ACTH依赖性CS的较好方法。
参考文献/References:
[1]Pecori Giraldi F.Recent challenges in the diagnosis of Cushing's syndrome [J].Horm Res,2009,71Suppl 1:123-127.
[2]Lad SP,Patil CG,Laws ER Jr,et al.The role of inferior petrosal sinus sampling in the diagnostic localization of Cushing's disease[J].Neurosurg Focus,2007,23:E2.
[3]Vilar L,Freitas Mda C,Faria M,et al.Pitfalls in the diagnosis of Cushing's syndrome [J].Arq Bras Endocrinol Metabol,2007,51:1207-1216.
[4]施海彬,李麟荪.岩下窦采样对柯兴氏综合征的诊断[J].国外医学.临床放射学分册,1997,6:340-344.
[5]Gazioglu N,Ulu MO,Ozlen F,et al.Management of Cushing's disease using cavernous sinus sampling:effectiveness in tumor lateralization[J].Clin Neurol Neurosurg,2008,110:333-338.
[6]Jagannathan J,Sheehan JP,Jane JA Jr.Evaluation and management of Cushing syndrome in cases of negative sellar magnetic resonance imaging[J].Neurosurg Focus,2007,23:E3.
[7]Kaskarelis IS,Tsatalou EG,Benakis SV,et al.Bilateral inferior petrosal sinuses sampling in the routine investigation of Cushing's syndrome :a comparison with MRI [J].AJR,2006,187:562-570.
[8]Jehle S,Walsh JE,Freda PU,et al.Selective use of bilateral inferior petrosal sinus sampling in patients with adrenocorticotropin-dependent Cushing's syndrome prior to transsphenoidal surgery[J].J Clin Endocrinol Metab,2008,93:4624-4632.
[9]Tsagarakis S,Vassiliadi D,Kaskarelis IS,et al.The application of the combined corticotropin-releasing hormone plus desmopressin stimulation during petrosal sinus sampling is both sensitive and specific in differentiating patients with Cushing's disease from patients with the occult ectopic adrenocorticotropin syndrome [J].J Clin Endocrinol Metab,2007,92:2080-2086.
[10]Gandhi CD,Meyer SA,Patel AB,et al.Neurologic compli-cations of inferior petrosal sinus sampling[J].AJNR,2008,29:760-765.
备注/Memo
- 备注/Memo:
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收稿日期:2009-12-11
基金项目:2008年上海高校选拔培养优秀青年教师科研专项基金(jdy08018)、上海市重点学科建设项目(S30203)
更新日期/Last Update:
2010-05-15