[1]李海伟,徐克,杨柯,等.可降解AZ31镁合金支架在兔腹主动脉的降解性能研究[J].介入放射学杂志,2010,(04):315.
LI Haiwei,XU Ke,YANG Ke,et al.The degradation performance of AZ31bioabsorbable magnesium alloy stent implanted in the abdominal aorta of rabbits[J].journal interventional radiology,2010,(04):315.
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可降解AZ31镁合金支架在兔腹主动脉的降解性能研究()
《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]
- 卷:
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- 期数:
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2010年04期
- 页码:
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315
- 栏目:
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实验研究
- 出版日期:
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2010-04-15
文章信息/Info
- Title:
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The degradation performance of AZ31bioabsorbable magnesium alloy stent implanted in the abdominal aorta of rabbits
- 作者:
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李海伟; 徐克; 杨柯; 等
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110001沈阳中国医科大学附属第一医院介入放射科(李海伟、徐克、刘静、夏永辉、韩洪波、洪铎);中国科学院金属研究所(杨柯、张炳春、郑丰、谭丽丽、颜廷亭)
- Author(s):
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LI Hai-wei; XU Ke ; YANG Ke ; LIU Jing; ZHANG Bin-chun; XIA Yong-hui ; ZHENG Feng; HAN Hong-bo; TAN Li-li; HONG Duo; YAN Ting-ting.
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First Affiliated Hospital of China Medical University,Shenyang110001,China
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- 关键词:
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可降解镁合金支架; 兔腹主动脉; 降解
- 分类号:
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R454.4
- 摘要:
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目的初步评价可降解AZ31镁合金支架在兔主动脉的降解性能。方法将12枚可降解AZ31镁合金支架置入12只新西兰大白兔腹主动脉中。分别于术后1个月(n=3)、2个月(n=3)、3个月(n=3)及4个月(n=3)处死动物。对支架段血管进行X线照相及病理检查。结果12只实验兔在随访期存活良好。X线照相及病理显示1个月时支架形态完整,扩张完全;2个月时支架部分支杆降解断裂,失去支撑作用;3个月时大部分支架支杆降解,4个月时所有支架完全降解。支架在兔主动脉中完全降解所需时间为104.5d。结论可降解AZ31镁合金支架在兔主动脉中2个月内失去支撑作用,延长支撑时间是未来的研究方向
参考文献/References:
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备注/Memo
- 备注/Memo:
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收稿日期:2009-11-25
基金项目:高等学校博士点基金(NO.20070159011)
更新日期/Last Update:
2010-04-15