[1]陈世壮,张波绪,方晓敏,等.125Ⅰ放射性粒子植入联合吉西他滨顺铂方案治疗老年非小细胞肺癌[J].介入放射学杂志,2008,(03):197.
 CHEN Shizhuang,ZHANG Boxu,FANG Xiaomin,et al.implantation combined with chemotherapy of GP regimens for non-small cell lung cancer in elder patients[J].journal interventional radiology,2008,(03):197.
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125 Ⅰ放射性粒子植入联合吉西他滨顺铂方案治疗老年非小细胞肺癌()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2008年03期
页码:
197
栏目:
非血管介入
出版日期:
2008-03-15

文章信息/Info

Title:
implantation combined with chemotherapy of GP regimens for non-small cell lung cancer in elder patients
作者:
陈世壮张波绪方晓敏
264200山东威海市解放军第四O四医院肿瘤血液科
Author(s):
CHEN Shi-zhuangZHANG Bo-xuFANG Xiao-minBAI Yan-chunZHANG Yan-xia.
Department of Oncology and Hematology,404Hospital,of PLA,Weihai264200,China
关键词:
肺肿瘤碘放射性同位素介入放射学近距离放疗综合治疗
分类号:
R437.2
文献标志码:
A
摘要:
目的评价 125 Ⅰ放射性粒子植入联合GP方案治疗老年非小细胞肺癌(NSCLC)的可行性、安全性及疗效。方法40例老年NSCLC中,初治24例,复治16例,均行CT引导下瘤体内 125 Ⅰ粒子植入后3~5d予GP方案:GEM1000mg /m 2 ,静脉滴注30min,第1、8、15天;DDP30mg /m 2 ,静脉滴注,第1~3d,28d为1个周期,化疗2~4个周期。粒子植入后2个月(即化疗2周期后)进行近期疗效及不良反应评价。结果 125 Ⅰ放射性粒子植入2个月后,40例患者全部可评价疗效。全组CR9例,PR23例,SD5例,PD3例,总有效率80.0%。初治组24例中,CR6例,PR14例,SD3例,PD1例,有效率83.3%;复治组16例中,CR3例,PR9例,SD2例,PD2例,有效率75.0%,两组差异无统计学意义(P>0.05)。结论 125 Ⅰ放射性粒子植入联合GP方案化疗对不能手术的老年NSCLC患者是一种安全、可行、有效的治疗方法。

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2007-10-31
更新日期/Last Update: 2008-03-15