[1]高 谦,李宝福,刘 冰,等.CT引导下脉冲射频联合连续神经阻滞治疗顽固性带状疱疹后神经痛的临床疗效研究[J].介入放射学杂志,2024,33(03):264-268.
 GAO Qian,LI Baofu,LIU Bing,et al.CT-guided pulsed radiofrequency combined with continuous nerve block for the treatment of refractory postherpetic neuralgia: a clinical study[J].journal interventional radiology,2024,33(03):264-268.
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CT引导下脉冲射频联合连续神经阻滞治疗顽固性带状疱疹后神经痛的临床疗效研究()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年03
页码:
264-268
栏目:
非血管介入
出版日期:
2024-03-27

文章信息/Info

Title:
CT-guided pulsed radiofrequency combined with continuous nerve block for the treatment of refractory postherpetic neuralgia: a clinical study
作者:
高 谦 李宝福 刘 冰 王春满 李 琳
Author(s):
GAO Qian LI Baofu LIU Bing WANG Chunman LI Lin.
Department of Pain Management, Hengshui Municipal People’s Hospital(Harrison International Peace Hospital), Hengshui, Hebei Province 053000, China
关键词:
【关键词】 带状疱疹后神经痛脉冲射频连续神经阻滞高迁移率族蛋白B1白细胞介素-1β白细胞介素-10
文献标志码:
A
摘要:
【摘要】 目的 探究CT引导下脉冲射频联合连续神经阻滞治疗顽固性带状疱疹后神经痛(PHN)的临床疗效。方法 选取2021年1月至2023年1月本院收治的208例顽固性PHN患者为对象,随机数表法分为联合组和对照组,每组各104例。对照组接受CT引导下脉冲射频治疗,联合组在对照组的基础上行连续硬膜外神经阻滞治疗。比较两组患者不同时间点疼痛情况、临床有效率、镇痛补救情况、睡眠质量,
血清高迁移率族蛋白B1(HMGB1)、白细胞介素-1β(IL-1β)和白细胞介素-10(IL-10)水平。结果 随访期间,4例患者失访。最终纳入联合组103例,对照组101例。联合组治疗总有效率为89.32%,明显高于对照组的78.22%(P<0.05)。患者疼痛视觉模拟量表(VAS)评分、阿森斯失眠量表(AIS)评分的时间、组间、时间与组间交互效应差异均具有统计学意义(P<0.05);治疗后1、2、4周联合组VAS、AIS评分均低于对照组(P<0.05);联合组镇痛补救次数低于对照组,曲马多使用剂量少于对照组(P<0.05);治疗后4周联合组血清HMGB1、IL-1β、IL-10水平均低于对照组(P<0.05)。结论 CT引导下脉冲射频联合连续神经阻滞治疗顽固性PHN,能有效减轻神经炎性损伤,改善患者疼痛症状,提高睡眠质量,其镇痛效果及临床疗效优于单纯使用CT引导下脉冲射频疗法。

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备注/Memo

备注/Memo:
(收稿日期:2023- 05- 10)
(本文编辑:茹 实)
更新日期/Last Update: 2024-03-27