[1]石 静,谢 军,袁玉山,等.氢吗啡酮静脉自控镇痛对瘢痕妊娠患者辅助行子宫动脉栓塞术后镇痛的有效性和安全性[J].介入放射学杂志,2024,33(03):240-244.
 SHI Jing,XIE Jun,YUAN Yushan,et al.The efficacy and safety of hydromorphone patients-controlled intravenous analgesia in patients with scar pregnancy after uterine artery embolization[J].journal interventional radiology,2024,33(03):240-244.
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氢吗啡酮静脉自控镇痛对瘢痕妊娠患者辅助行子宫动脉栓塞术后镇痛的有效性和安全性()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
33
期数:
2024年03
页码:
240-244
栏目:
血管介入
出版日期:
2024-03-27

文章信息/Info

Title:
The efficacy and safety of hydromorphone patients-controlled intravenous analgesia in patients with scar pregnancy after uterine artery embolization
作者:
石 静 谢 军 袁玉山 李琳娜 陈 颍
Author(s):
SHI Jing XIE Jun YUAN Yushan LI Linna CHEN Ying.
Department of Interventional Radiology, Fuyang Municipal People’s Hospital, Fuyang, Anhui Province 236000, China
关键词:
【关键词】 氢吗啡酮 瘢痕妊娠 子宫动脉栓塞术 静脉自控镇痛 镇痛
文献标志码:
A
摘要:
【摘要】 目的 评价氢吗啡酮静脉自控镇痛(pcatient- controlled intravenous analgesia,PCIA)对瘢痕妊娠患者辅助行子宫动脉栓塞术(uterine artery embolization,UAE)术后镇痛的有效性和安全性。 方法 选取2021年1月至2022年9月在阜阳市人民医院瘢痕妊娠行UAE辅助治疗的患者116例。依据UAE术后PCIA药物不同,随机分为观察组、对照组,每组为58例。分别于手术开始前10 min静注氢吗啡酮2 mg(观察组)和舒芬太尼2 μg/kg(对照组),并连接患者自控静脉镇痛泵。观察组:氢吗啡酮10 mg+氟比洛芬酯100 mg+0.9%氯化钠注射液100 mL配置至镇痛泵中;对照组:舒芬太尼2 μg/kg+氟比洛芬酯100 mg+0.9%氯化钠注射液100 mL配置至镇痛泵中。记录两组患者UAE术后0.5、4、8、12、24、48 h视觉模拟量表(visual analogue scale,VAS)评分、布鲁格曼舒适度量表(Bruggrmann comfort scale,BCS)评分,术后48 h内镇痛泵按压次数、镇痛药物用量、不良反应及术后并发症发生率。结果 观察组术后0.5 h VAS评分与对照组比较,差异无统计学意义(P>0.05),而术后4、8、12、24、48 h VAS评分明显低于对照组,差异有统计学意义(均P<0.05)。观察组术后0.5、4、8、12、24、48 h BCS评分明显高于对照组,差异有统计学意义(P<0.05)。观察组术后48 h内镇痛泵按压次数、镇痛药物用量低于对照组,差异有统计学意义(均P<0.05)。两组患者嗜睡、皮肤瘙痒、低氧或呼吸抑制等并发症比较差异无统计学差异(P>0.05),而两组患者不良反应发生率比较差异有统计学差异(P<0.05)。结论 氢吗啡酮和舒芬太尼PCIA有助于缓解瘢痕妊娠子宫动脉栓塞术术后疼痛,但氢吗啡酮对比舒芬太尼可明显降低术后VAS评分、提高术后BCS评分,术后48 h内镇痛泵按压次数及镇痛药物用量减少、不良反应发生率较低,有一定的推广价值。

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备注/Memo

备注/Memo:
(收稿日期:2023- 05- 23)
(本文编辑:茹 实)
更新日期/Last Update: 2024-03-27