[1]孙沁瑜,邓毅凡,方 震,等.全身炎症反应指数和全身免疫炎症指数对非瓣膜性心房颤动患者左心耳封堵术后预后预测价值[J].介入放射学杂志,2026,(04):377-384.[doi:10.3969/j.issn.1008-794X.2026.04.006 ]
　SUN Qinyu,DENG Yifan,FANG Zhen,et al.The predictive value of the systemic inflammatory response index and systemic immune inflammation index for the postoperative prognosis of patients with non-valvular atrial fibrillation undergoing left atrial appendage closure surgery[J].J Intervent Med,2026,(04):377-384.[doi:10.3969/j.issn.1008-794X.2026.04.006 ]
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全身炎症反应指数和全身免疫炎症指数对非瓣膜性心房颤动患者左心耳封堵术后预后预测价值()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2026年04
页码:
377-384
栏目:
心脏介入
出版日期:
2026-04-15

文章信息/Info

Title:
The predictive value of the systemic inflammatory response index and systemic immune inflammation index for the postoperative prognosis of patients with non-valvular atrial fibrillation undergoing left atrial appendage closure surgery
文章编号:
1008-794X(2026)-004-0377-08
作者:
孙沁瑜; 邓毅凡; 方 震; 纪 军; 何胜虎; 张 晶
225001 江苏扬州 扬州大学附属苏北人民医院(江苏省苏北人民医院)心血管内科(孙沁瑜、邓毅凡、方 震、纪 军、何胜虎、张 晶); 扬州大学医学院研究生院(孙沁瑜、邓毅凡、张 晶)
Author(s):
SUN Qinyu; DENG Yifan; FANG Zhen; JI Jun; HE Shenghu; ZHANG Jing.
Department of Cardiovascular Medicine,Affiliated Northern Jiangsu People's Hospital of Yangzhou University,Yangzhou,Jiangsu Province 225001,China
关键词:
全身炎症反应指数;  全身免疫炎症指数;  非瓣膜病心房颤动;  左心耳封堵术;  主要不良心脑血管事件;  预测价值
分类号:
R541.75
DOI:
10.3969/j.issn.1008-794X.2026.04.006
文献标志码:
A
摘要:
目的 探讨非瓣膜性心房颤动(non-valvular atrial fibrillation,NVAF)患者全身炎症反应指数(systemic inflammation response index,SIRI)和全身免疫炎症指数(systemic immune-inflammation index,SII)与左心耳封堵术(left atrial appendage closure,LAAC)预后的相关性。方法 回顾性纳入2019年至2023年在苏北人民医院接受LAAC的254例NVAF患者。根据LAAC后是否发生主要心脑血管不良事件(major adverse cardiovascular and cerebrovascular events,MACCE),将患者分为MACCE组(n=52)和非MACCE组(n=202)。Cox比例风险回归模型分析发生MACCE危险因素。结果 两组间年龄、2型糖尿病、抗血小板药、白细胞计数、中性粒细胞计数、单核细胞计数、纤维蛋白原、SII、SIRI比较差异均有统计学意义。Cox多因素回归分析结果显示,2型糖尿病史、年龄、SII和SIRI是NVAF患者行LAAC后发生MACCE的独立危险因素。绘制受试者工作特征曲线显示,SII、SIRI及两者联合预测NVAF患者行LAAC后发生MACCEs的曲线下面积分别为0.694、0.717、0.731。Kaplan-Meier生存曲线显示,SII、SIRI及两组联合值越高,发生MACCEs风险越高。结论 SIRI、SII及两者联合与NVAF患者行LAAC后发生MACCEs有显著相关性,具有一定的预测价值,值得临床推广应用。

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(收稿日期:2025-04-07)
(本文编辑:谷 珂)

相似文献/References:

[1]杨 晶,树成森,徐 杰,等.术前全身免疫炎症指数对胆道支架联合125I粒子植入治疗肝外胆管癌预后的判断价值[J].介入放射学杂志,2023,32(12):1221.
　YANG Jing,SHU Chengsen,XU Jie,et al.The clinical value of preoperative systemic immune-inflammation index in predicting the prognosis of patients with extrahepatic cholangiocarcinoma treated with biliary stenting combined with 125I seeds implantation[J].J Intervent Med,2023,32(04):1221.

备注/Memo

备注/Memo:
基金项目: 江苏省研究生科研与实践创新计划项目(SJCX25-2401)
通信作者: 张 晶 E-mail:zhangjingyjs@163.com
更新日期/Last Update: 2026-04-25