[1]冯宇旋,王金志,李新成,等.球囊肺动脉成形术治疗慢性血栓栓塞性肺动脉高压对肾功能的作用[J].介入放射学杂志,2025,34(02):160-165.
 FENG Yuxuan,WANG Jinzhi,LI Xincheng,et al.The influence of balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension on renal functions[J].journal interventional radiology,2025,34(02):160-165.
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球囊肺动脉成形术治疗慢性血栓栓塞性肺动脉高压对肾功能的作用()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
34
期数:
2025年02
页码:
160-165
栏目:
临床研究
出版日期:
2025-02-17

文章信息/Info

Title:
The influence of balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension on renal functions
作者:
冯宇旋王金志李新成张帅高倩王同生毛毅敏谢万木 翟振国黄强
Author(s):
FENG YuxuanWANG JinzhiLI XinchengZHANG ShuaiGAO QianWANG TongshengMAO YiminXIE WanmuZHAI ZhenguoHUANG Qiang.
Department of Pulmonary and Critical Care Medicine,First Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan Province 471000,China
关键词:
【关键词】慢性血栓栓塞性肺动脉高压球囊肺动脉成形术对比剂肾病肾功能肾小球滤过率
文献标志码:
A
摘要:
【摘要】目的评估球囊肺动脉成形术(balloon pulmonary angioplasty,BPA)治疗慢性血栓栓塞性肺动脉高压(chronic thromboembolic pulmonary hypertension,CTEPH)患者后对比剂肾病(contrast-induced nephropathy,CIN)的发生率及BPA对肾功能的影响。方法收集2018年12月至2022年5月于中日友好医院行BPA治疗的143例 CTEPH患者的临床信息、血流动力学指标、BPA术前1周内及术后48~72 h内的血肌酐浓度,对比每次BPA前后血肌酐及肾小球滤过率(estimated glomerular filtration rate,eGFR)变化,评估CIN发生率及危险因素,分析首次及末次BPA治疗后的血流动力学、血肌酐及eGFR变化。结果纳入115例CTEPH患者,共行BPA 192例次,其中男性88例次,女性103例次。每次BPA使用对比剂剂量为(145.58±47.26) mL。BPA术后共有12例患者发生13例次CIN,发生率为6.8%。CIN患者的基线特征及肾功能与非CIN患者相比差异无统计学意义(P>0.05);血流动力学指标中,混合静脉血氧饱和度(mixed venous oxygen saturation,SvO2)在CIN患者中更低(58.58%±10.38%比66.15%±8.02%,P=0.002),其他血流动力学指标两组差异无统计学意义(P>0.05)。CTEPH患者在不同频次的BPA治疗前后血肌酐及eGFR对比差异无统计学意义(P>0.05),经数次BPA治疗后,末次肾功能指标血肌酐[(78.09±18.760) μmol/L比(82.26±21.37) μmol/L,P<0.001]和eGFR[(86.08±21.22) mL/(min·1.73 m2)比(82.07±22.05) mL/(min·1.73 m2),P=0.007]较基线值均得到显著改善。结论BPA治疗CTEPH患者后可发生对比剂肾病,多次BPA治疗后随着临床症状及血流动力学的改善,肾功能也显著改善。

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相似文献/References:

[1]王金志,陶新曹,谢万木,等.球囊肺动脉成形术治疗近端慢性血栓栓塞性肺动脉高压的安全性和有效性[J].介入放射学杂志,2023,32(08):746.
 WANG Jinzhi,TAO Xincao,XIE Wanmu,et al.The safety and efficacy of balloon pulmonary angioplasty in the treatment of proximal-type chronic thromboembolic pulmonary hypertension[J].journal interventional radiology,2023,32(02):746.

备注/Memo

备注/Memo:
(收稿日期:2024-02-27)
(本文编辑:新宇)
更新日期/Last Update: 2025-02-17