[1]冯二军,李 姮,李永辉,等.冠状动脉CTA血流储备分数对冠心病患者PCI术后主要不良心脏事件的评估价值[J].介入放射学杂志,2026,(05):533-537.[doi:10.3969/j.issn.1008-794X.2026.05.012 ]
　FENG Erjun,LI Heng,LI Yonghui,et al.The clinical value of coronary CTA fractional flow reserve in predicting major adverse cardiac events in patients with coronary heart disease after PCI[J].J Intervent Med,2026,(05):533-537.[doi:10.3969/j.issn.1008-794X.2026.05.012 ]
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冠状动脉CTA血流储备分数对冠心病患者PCI术后主要不良心脏事件的评估价值()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2026年05
页码:
533-537
栏目:
临床研究
出版日期:
2026-05-25

文章信息/Info

Title:
The clinical value of coronary CTA fractional flow reserve in predicting major adverse cardiac events in patients with coronary heart disease after PCI
文章编号:
1008-794X(2026)-005-0533-05
作者:
冯二军;  李 姮;  李永辉;  何 峰
300140 天津 天津第四中心医院心内三科
Author(s):
FENG Erjun; LI Heng; LI Yonghui; HE Feng.Section Ⅲ; Department of Cardiology; Tianjin Fourth Central Hospital; Tianjin 300140; China
Corresponding author:HE Feng,E-mail:13821831029@163.com
关键词:
冠心病;  经皮冠状动脉介入治疗;  计算机断层扫描血管成像;  血流储备分数;  主要不良心脏事件
分类号:
R541.4
DOI:
10.3969/j.issn.1008-794X.2026.05.012
文献标志码:
B
摘要:
目的 探究基于CT的血流储备分数(CT-based flow fraction reserve,CT-FFR)对冠心病患者经皮冠状动脉介入(percutaneous coronary intervention,PCI)术后主要不良心脏事件(major adverse cardiac events,MACE)的预测价值。方法 采用回顾性队列研究设计,纳入2023年1月至2024年9月天津第四中心医院收治的冠心病患者717例,均接受PCI治疗,且术前1周内行冠状动脉计算机断层血管成像(coronary computed tomography angiography,CCTA)检查。根据术后12个月的随访结果,将患者分为MACE组与非MACE组,比较两组患者基线临床资料、冠脉病变特征、PCI手术情况及术前CT-FFR值。多因素logistic回归分析PCI术后发生MACE的独立危险因素,采用受试者工作特征曲线下面积(area under the curve,AUC)评估CT-FFR对MACE的预测效能。结果 717例患者随访期间共发生MACE事件86例(11.99%)。MACE组年龄、合并糖尿病比例、高敏C反应蛋白(high-sensitivity C-reactive protein,hs-CRP)水平、SYNTAX评分均高于非MACE组(P<0.001),术前CT-FFR低于非MACE组(P<0.001)。多因素logistic回归分析显示,糖尿病(OR=2.138,95%CI:1.265～3.616,P=0.005)及术前CT-FFR(OR=0.002,95%CI:0.000～0.028,P<0.001)是PCI术后发生MACE的独立预测因子。ROC曲线分析结果显示,术前CT-FFR预测PCI术后MACE的AUC为0.838(95%CI:0.795～0.882,P<0.001),最佳截断值为0.78,敏感度、特异度分别为0.83、0.78。结论 术前冠状动脉CT-FFR是冠心病患者PCI术后发生MACE的独立预测因子,对于术后风险分层及指导患者管理具有重要的临床价值。

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(收稿日期:2025-11-03)
(本文编辑:新 宇)

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备注/Memo

备注/Memo:
通信作者: 何 峰 E-mail:13821831029@163.com
更新日期/Last Update: 2026-05-25