[1]段正新,王俊超,赵 卫.肝动脉灌注化疗治疗晚期肝细胞癌合并门静脉癌栓的研究进展[J].介入放射学杂志,2025,34(04):341-346.[doi:10.3969/j.issn.1008-794X.2025.04.001]
 DUAN Zhengxin,WANG Junchao,ZHAO Wei..Research progress in hepatic arterial perfusion chemotherapy for advanced hepatocellular carcinoma complicated by portal vein tumor thrombus[J].J Intervent Med,2025,34(04):341-346.[doi:10.3969/j.issn.1008-794X.2025.04.001]
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肝动脉灌注化疗治疗晚期肝细胞癌合并门静脉癌栓的研究进展()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
34
期数:
2025年04
页码:
341-346
栏目:
专论
出版日期:
2025-04-25

文章信息/Info

Title:
Research progress in hepatic arterial perfusion chemotherapy for advanced hepatocellular carcinoma complicated by portal vein tumor thrombus
文章编号:
1008-794X(2025)-004-0341-06
作者:
段正新 王俊超 赵 卫
650032 云南昆明 昆明医科大学第一附属医院医学影像科
Author(s):
DUAN ZhengxinWANG JunchaoZHAO Wei.
Department of Medical Imaging,First Affiliated Hospital of Kunming Medical University,Kunming,Yunnan Province 650032,China
关键词:
肝细胞癌 门静脉癌栓 肝动脉灌注化疗
分类号:
P735.7
DOI:
10.3969/j.issn.1008-794X.2025.04.001
文献标志码:
A
摘要:
肝细胞癌(HCC)容易侵犯门静脉形成门静脉癌栓(PVTT),尽管近年来HCC的治疗取得了显著发展,但合并PVTT的患者治疗选择有限预后差。肝动脉灌注化疗(HAIC)是一种将局部治疗与全身抗肿瘤作用相结合的治疗方法,研究表明HAIC对晚期HCC合并PVTT的患者有生存获益,被认为是晚期HCC有效的局部治疗方法,特别是在Vp3-4型患者中疗效更为明显。全身治疗是晚期HCC的主要治疗方法,但是多样性的HAIC联合靶向及免疫治疗有望成为HCC合并重度PVTT一种更有效的治疗选择,通过转化治疗有可能实现无瘤状态,让晚期HCC患者长期生存。该文旨在总结HAIC治疗晚期HCC合并PVTT的研究进展。

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(收稿日期:2024-04-11)
(本文编辑:茹 实)

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备注/Memo

备注/Memo:
基金项目: 云南省放射与治疗临床医学研究中心专项资金子课题实体瘤及血管病变介入诊疗机制与技术的研发和推广基金资助项目(202102AA100067)
通信作者: 赵 卫 E-mail:kyyyzhaowei@foxmail.com
更新日期/Last Update: 2025-04-25