[1]刘钦晨,贾振宇,赵林波,等.梗死核心容积预测急性前循环大血管闭塞患者机械取栓术后出血转化的价值[J].介入放射学杂志,2021,30(08):756-760.
 LIU Qinchen,JIA Zhenyu,ZHAO Linbo,et al.The clinical value of infarction core volume in predicting hemorrhagic transformation in patients with acute anterior circulatory large vessel occlusion after receiving mechanical thrombectomy[J].journal interventional radiology,2021,30(08):756-760.
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梗死核心容积预测急性前循环大血管闭塞患者机械取栓术后出血转化的价值()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
30
期数:
2021年08
页码:
756-760
栏目:
神经介入
出版日期:
2021-08-25

文章信息/Info

Title:
The clinical value of infarction core volume in predicting hemorrhagic transformation in patients with acute anterior circulatory large vessel occlusion after receiving mechanical thrombectomy
作者:
刘钦晨 贾振宇 赵林波 曹月洲 周春高 施海彬 刘 圣
Author(s):
LIU Qinchen JIA Zhenyu ZHAO Linbo CAO Yuezhou ZHOU Chungao SHI Haibin LIU Sheng.
Department of Interventional Radiology, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210029, China
关键词:
【关键词】 急性缺血性脑卒中 机械取栓术 出血转化 梗死核心容积
文献标志码:
A
摘要:
【摘要】 目的 探讨急性前循环大血管闭塞患者机械取栓术后梗死核心容积与出血转化(HT)的关系。 方法 回顾性分析2019年10月至2020年2月在南京医科大学第一附属医院接受机械取栓术治疗前循环大血管闭塞的急性缺血性脑卒中(AIS)患者临床和影像学资料。根据欧洲急性脑卒中协作研究(ECASS)Ⅱ标准,将患者分为HT组和Non-HT组,同时根据术后是否发生实质性血肿(PH)分为PH组和Non-PH组,分别比较两组患者临床资料。采用多因素logistic回归分析评估HT和PH独立危险因素,受试者工作特征曲线(ROC)分析梗死核心容积预测HT和PH的效能。 结果 共76例患者纳入分析。HT组26例, Non-HT组50例;PH组10例,Non-PH组66例。HT组梗死核心容积、美国国立卫生研究院卒中量表(NIHSS)评分及血糖水平均高于Non-HT组(P<0.05)。PH组梗死核心容积、NIHSS评分均高于Non-PH组(P<0.05)。多因素logistic回归分析显示,梗死核心容积较大是机械取栓术后发生HT的独立危险因素(OR=1.032,95%CI=1.003~1.061, P=0.028),也是发生PH的独立危险因素(OR=1.045,95%CI=1.007~1.085,P=0.021)。梗死核心容积预测HT的灵敏度为57.7%,特异度为72.0%,ROC曲线下面积(AUC)为0.658,预测值为13.5 mL;预测PH的灵敏度为54.5%,特异度为93.8%,AUC为0.755,预测值为36 mL。 结论 梗死核心容积较大是AIS患者机械取栓术后发生HT、PH的独立危险因素。梗死核心容积对AIS患者取栓术后HT具有预测价值。

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备注/Memo

备注/Memo:
 (收稿日期:2020-08-24)
(本文编辑:边 佶)
更新日期/Last Update: 2021-08-18