[1]鲁海涛,邓 波,刘卫东,等.大脑前动脉A1段发育不良与前交通动脉瘤的关系分析 [J].介入放射学杂志,2020,29(12):1240-1244.
　LU Haitao,DENG Bo,LIU Weidong,et al.The relationship of congenital A1 segment hypoplasia of anterior cerebral artery to anterior communicating artery aneurysm： a clinical analysis[J].journal interventional radiology,2020,29(12):1240-1244.
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大脑前动脉A1段发育不良与前交通动脉瘤的关系分析
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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年12
页码:
1240-1244
栏目:
临床研究
出版日期:
2020-12-25

文章信息/Info

Title:
The relationship of congenital A1 segment hypoplasia of anterior cerebral artery to anterior communicating artery aneurysm： a clinical analysis
作者:
鲁海涛;  邓 波;  刘卫东;  顾文权;  孟令平;  李明华
Author(s):
LU Haitao;  DENG Bo;  LIU Weidong;  GU Wenquan;  MENG Lingping;  LI Minghua.
Department of Interventional Radiology， Affiliated Sixth People’s Hospital of Shanghai Jiao Tong University， Shanghai 200233， China
关键词:
【关键词】 前交通动脉;  颅内动脉瘤;  发育不良;  风险因素;  破裂
文献标志码:
A
摘要:
【摘要】 目的 探讨大脑前脑动脉A1段先天性发育不良对前交通动脉（ACoA）动脉瘤形成和破裂风险的影响。方法 回顾性分析2005年1月至2015年12月接受脑血管造影的253例ACoA动脉瘤患者临床资料。单因素和多因素logistic回归模型用于分析患者年龄、性别、A1段发育不良和动脉瘤大小等风险因素，预测ACoA动脉瘤破裂可能相关因素。结果 253例患者共确诊253枚ACoA动脉瘤，其中218枚（86.2%）动脉瘤破裂，35枚（13.8%）未破裂。69.6%（176/253）动脉瘤最大径＜5 mm，其中146枚（83.0%）破裂。所有患者中141例（55.7%）表现出A1段发育不良，其中右侧106例（41.9%），左侧仅35例（13.8%）。单因素分析显示破裂与未破裂动脉瘤患者A1段发育不良患病率比较，A1段发育不良与患者年龄和动脉瘤大小比较，差异均无统计学意义（P＞0.05）；多因素logistic回归分析显示，动脉瘤大小（OR=3.483，95%CI=1.233～9.837，P=0.018）和患者年龄（＜65岁）（OR=0.150，95%CI=0.068～0.330，P＜0.001）是ACoA动脉瘤破裂的独立预测因素。结论 ACoA动脉瘤破裂风险较高，且通常在形态较小（＜5 mm）时也易破裂。大脑前动脉A1段发育不良可能是ACoA动脉瘤形成的潜在危险因素，但它与动脉瘤大小和破裂风险无关。ACoA动脉瘤破裂的最强独立危险因素是年龄（＜65岁）和动脉瘤大小两个因素。

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备注/Memo

备注/Memo:
（收稿日期：2020- 06- 12）
（本文编辑：边 佶）
更新日期/Last Update: 2020-12-16