[1]张利捷,梁斌.免疫检查点阻断与肝癌化疗栓塞[J].介入放射学杂志,2020,29(04):419-422.
 ZHANG Lijie,LIANG Bin..Immune checkpoint inhibition and chemoembolization of hepatocellular carcinoma[J].journal interventional radiology,2020,29(04):419-422.
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免疫检查点阻断与肝癌化疗栓塞()

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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
29
期数:
2020年04
页码:
419-422
栏目:
综述
出版日期:
2020-05-08

文章信息/Info

Title:
Immune checkpoint inhibition and chemoembolization of hepatocellular carcinoma
作者:
张利捷梁斌
Author(s):
ZHANG Lijie LIANG Bin.
Department of Radiology, Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province 430022, China
关键词:
【关键词】 化疗栓塞免疫检查点程序性细胞死亡蛋白1细胞毒T淋巴细胞相关抗原4肝细胞癌
文献标志码:
A
摘要:
【摘要】 肝癌化疗栓塞通过动脉内灌注化疗药和阻断肿瘤血供诱导大量肿瘤细胞死亡,但它对肿瘤免疫的影响尚不明确。免疫检查点抑制疗法是目前肿瘤免疫治疗的主导方法,对某些特定癌症疗效显著,但并不是对所有癌症普遍有效。早期研究表明免疫检查点阻断与消融或栓塞联合治疗肝癌具有协同抗肿瘤作用。本文就肝癌免疫学特点、免疫检查点抑制剂及其与化疗栓塞联合治疗作一综述。

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备注/Memo

备注/Memo:
(收稿日期:2019-02-10)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2020-05-06