[1]郑 晖,杨维竹,黄 宁,等.不同直径覆膜支架行经颈静脉肝内门体分流术治疗管胃底静脉曲张破裂出血 [J].介入放射学杂志,2018,27(02):167-171.
 ZHENG Hui,YANG Weizhu,HUANG Ning,et al.Transjugular intrahepatic portosystemic shunt by using covered stents of different diameters for the treatment of esophagogastric varices rupture with bleeding[J].journal interventional radiology,2018,27(02):167-171.
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不同直径覆膜支架行经颈静脉肝内门体分流术治疗管胃底静脉曲张破裂出血


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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
27
期数:
2018年02期
页码:
167-171
栏目:
临床研究
出版日期:
2018-02-25

文章信息/Info

Title:
Transjugular intrahepatic portosystemic shunt by using covered stents of different diameters for the treatment of esophagogastric varices rupture with bleeding
作者:
郑 晖 杨维竹 黄 宁 黄兢姚 郑曲彬 江 娜 吴正忠 申 权 柯 坤
Author(s):
ZHENG Hui YANG Weizhu HUANG Ning HUANG Jingyao ZHENG Qubin JIANG Na WU Zhengzhong SHEN Quan KE Kun
Department of Interventional Radiology, Affiliated Union Hospital, Fujian Medical University, Fuzhou, Fujian Province 350001, China
关键词:
【关键词】 门体分流术经颈静脉肝内 食管胃底静脉曲张 出血 支架直径
文献标志码:
A
摘要:
【摘要】 目的 评价不同直径覆膜支架行经颈静脉肝内门体分流术(TIPS)治疗食管胃底静脉曲张破裂出血(EGVB)的疗效与安全性。方法 收集2010年12月至2015年2月因EGVB接受TIPS治疗的68例肝硬化门静脉高压症患者临床资料,其中30例使用直径7 mm覆膜支架(小支架组),38例使用直径8 mm覆膜支架(大支架组)。采用Kaplan- Meier法分析两组患者累积无消化道再出血率、分流道通畅率和生存率,进一步组间比较采用Log- rank检验,肝性脑病发生率比较采用χ2检验。结果 68例患者手术成功率为100%。术后随访0.1~52.3个月,平均(19.4±16.0)个月。术后3、6、12个月累积无消化道再出血率,在小支架组分别为86.54%、79.30%、74.90%,大支架组分别为91.87%、85.93%、81.63%,两组差异无统计学意义(χ2=0.05,P=0.83);分流道累积通畅率,在小支架组分别为95.00%、80.19%、70.17%,大支架组分别为96.15%、91.97%、81.07%,两组差异无统计学意义(χ2=0.40,P=0.53);术后3、12、24、48个月累积生存率,在小支架组分别为93.33%、86.67%、75.11%、64.38%,大支架组分别为97.37%、94.23%、88.68%、76.02%,两组差异无统计学意义(χ2=2.21,P=0.14);术后出现肝性脑病15例(15/68,22.06%),小支架组、大支架组发生率分别为20.00%(6/30)、23.68%(9/38),差异无统计学意义(χ2=0.13,P=0.72)。结论 与直径7 mm覆膜支架相比,采用直径8 mm覆膜支架行TIPS术治疗EGVB并未提高疗效及降低肝性脑病发生率。

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备注/Memo

备注/Memo:
(收稿日期:2017-03-10)
(本文编辑:边 佶)
更新日期/Last Update: 2018-02-24