[1]王斯妮,贾中芝,胡红杰,等.钇-90微球的特性、放射栓塞的操作技术及安全防护——钇-90微球放射栓塞系列回顾(一) [J].介入放射学杂志,2017,(10):952-957.
 WANG Sini,JIA Zhongzhi,HU Hongjie,et al.Characteristics of yttrium- 90 microsphere, techniques and radiation safety of radioembolization procedure. A series review of radioembolization with yttrium- 90 microspheres(partⅠ)[J].journal interventional radiology,2017,(10):952-957.
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钇-90微球的特性、放射栓塞的操作技术及安全防护——钇-90微球放射栓塞系列回顾(一)



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《介入放射学杂志》[ISSN:1008-794X/CN:31-1796/R]

卷:
期数:
2017年10期
页码:
952-957
栏目:
讲 座
出版日期:
2017-10-25

文章信息/Info

Title:
Characteristics of yttrium- 90 microsphere, techniques and radiation safety of radioembolization procedure. A series review of radioembolization with yttrium- 90 microspheres(partⅠ)
作者:
王斯妮 贾中芝 胡红杰 赵 添 郑丽丽 王维平
Author(s):
WANG Sini JIA Zhongzhi HU Hongjie ZHAO Tian ZHENG Lili WANG Weiping
Department of Radiology, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province 325000, China
关键词:
【关键词】 钇-90 微球 辐射 防护
文献标志码:
A
摘要:
【摘要】 钇-90(90Y)微球放射栓塞是一种局部治疗方法,它将载有发射β射线的90Y树脂或玻璃微球选择性地注射到肝动脉。90Y微球随血流被阻塞在肿瘤血管床,其发出的射线对靶肿瘤具有细胞毒性作用。该方法的安全性和有效性已经在不可切除的肝脏恶性肿瘤患者中得到证实。本文作为90Y微球放射栓塞系列综述的第一部分,将讨论90Y和90Y微球的基本特性,90Y微球放射栓塞的基本操作方法,以及放射性安全与防护。

参考文献/References:

[1] Park HC, Seong J, Han KH, et al. Dose- response relationship in local radiotherapy for hepatocellular carcinoma[J]. Int J Radiat Oncol Biol Phys, 2002, 54: 150- 155.
[2] Dawson LA, Normolle D, Balter JM, et al. Analysis of radiation- induced liver disease using the Lyman NTCP model[J]. Int J Radiat Oncol Biol Phys, 2002, 53: 810- 821.
[3] Kennedy A, Nag S, Salem R, et al. Recommendations for radioembolization of hepatic malignancies using yttrium- 90 micro- sphere brachytherapy: a consensus panel report from the radioembo- lization brachytherapy oncology consortium[J]. Int J Radiat Oncol Biol Phys, 2007, 68: 13- 23.
[4] Lewin R, Hart HE, Greenberg J, et al. Biological studies on stable and radioactive rare earth compounds. Ⅲ. Distribution of radioactive yttrium in normal and ascites- tumor- bearing mice, and in cancer patients with serous effusions[J]. J Natl Cancer Inst, 1954, 15: 131- 143.
[5] Grady ED, Sale W, Nicolson WP Jr, et al. Intra- arterial radioisotopes to treat cancer[J]. Am Surg, 1960, 26: 678- 684.
[6] Ariel IM. Treatment of inoperable primary pancreatic and liver cancer by the intra- arterial administration of radioactive isotopes(90Y radiating microspheres)[J]. Ann Surg, 1965, 162: 267- 278.
[7] 颜志平, 赵惠扬, 林 贵. 放射性微球内放射治疗肝脏恶性肿瘤[J]. 国际放射医学核医学杂志, 1992, 10: 130- 134.
[8] 王斯妮, 颜志平. 90Y玻璃微球内放射治疗的实验研究和治疗肝癌的初步探讨[J]. 中华核医学杂志, 1992, 12: 220- 222.
[9] 颜志平. 钇-90玻璃微球肝动脉给药途径的实验研究[J]. 中华放射学杂志, 1993, 27: 47- 49.
[10] Yan ZP, Lin G, Zhao HY, et al. Yttrium- 90 glass microspheres injected via the portal vein. An experimental study[J]. Acta Radiol, 1993, 34: 395- 398.
[11] Yan ZP, Lin G, Zhao HY, et al. An experimental study and clinical pilot trails on yttrium- 90 glass microspheres via the hepatic artery for treatment of primary liver cancer[J]. Cancer, 1993, 72: 3210- 3215.
[12] 董宝玮, 梁 萍, 苏 莉, 等. 超声引导下肝癌介入性治疗的研究[J]. 临床医学影像杂志, 1996, 7: 71- 74.
[13] Mosconi C, Cappelli A, Pettinato C, et al. Radioembolization with yttrium- 90 microspheres in hepatocellular carcinoma: role and perspectives[J]. World J Hepatol, 2015, 7: 738- 752.
[14] Hilgard P, Hamami M, Fouly AE, et al. Radioembolization with yttrium- 90 glass microspheres in hepatocellular carcinoma: European experience on safety and long- term survival[J]. Hepato- logy, 2010, 52: 1741- 1749.
[15] Kooby DA, Egnatashvili V, Srinivasan S, et al. Comparison of yttrium- 90 radioembolization and transcatheter arterial chemoem- bolization for the treatment of unresectable hepatocellular carcinoma[J]. J Vasc Interv Radiol, 2010, 21: 224- 230.
[16] Salem R, Lewandowski R, Roberts C, et al. Use of yttrium- 90 glass microspheres(TheraSphere) for the treatment of unresectable hepatocellular carcinoma in patients with portal vein thrombosis[J]. J Vasc Interv Radiol, 2004, 15: 335- 345.
[17] Mazzaferro V, Sposito C, Bhoori S, et al. Yttrium- 90 radioembo- lization for intermediate- advanced hepatocellular carcinoma: a phase 2 study[J]. Hepatology, 2013, 57: 1826- 1837.
[18] Lau WY, Sangro B, Chen PJ, et al. Treatment for hepatocellular carcinoma with portal vein tumor thrombosis: the emerging role for radioembolization using yttrium- 90[J]. Oncology, 2013, 84:311- 318.
[19] Salem R, Lewandowski RJ, Mulcahy MF, et al. Radioembo- lization for hepatocellular carcinoma using yttrium- 90 micros- pheres: a comprehensive report of long- term outcomes[J]. Gastroen- terology, 2010, 138: 52- 64.
[20] Mulcahy MF, Lewandowski RJ, Ibrahim SM, et al. Radioembo- lization of colorectal hepatic metastases using yttrium- 90 micro- spheres[J]. Cancer, 2009, 115: 1849- 1858.
[21] Lewandowski RJ, Salem R. Yttrium- 90 radioembolization of hepatocellular carcinoma and metastatic disease to the liver[J]. Semin Intervent Radiol, 2006, 23: 64- 72.
[22] Lee EW, Alanis L, Cho SK, et al. Yttrium- 90 selective internal radiation therapy with glass microspheres for hepatocellular carcinoma: current and updated literature review[J]. Korean J Radiol, 2016, 17: 472- 488.
[23] Kallini JR, Gabr A, Salem R, et al. Transarterial radioembo- lization with yttrium- 90 for the treatment of hepatocellular carcinoma[J]. Adv Ther, 2016, 33: 699- 714.
[24] 尹帮顺, 李明起, 邓启民, 等. 90Y发生器的研究进展[J]. 同位素, 2009, 22: 187- 192.
[25] Yeong CH, Cheng MH, Ng KH. Therapeutic radionuclides in nuclear medicine: current and future prospects[J]. J Zhejiang Univ Sci B, 2014, 15: 845- 863.
[26] Stillwagon GB, Order SE, Guse C, et al. 194 hepatocellular cancers treated by radiation and chemotherapy combinations: toxicity and response: a Radiation Therapy Oncology Group Study[J]. Int J Radiat Oncol Biol Phys, 1989, 17: 1223- 1229.
[27] Nijsen JF, van het Schip AD, Hennink WE, et al. Advances in nuclear oncology: microspheres for internal radionuclide therapy of liver tumours[J]. Curr Med Chem, 2002, 9: 73- 82.
[28] 赵明强, 许书河. 放射性栓塞治疗肝癌用微球的研究进展[J]. 中国核科技报告, 2007, 2: 100- 110.
[29] Ariel IM. Radioactive isotopes for adjuvant cancer therapy: animal experimentation and preliminary results in human application[J]. Arch Surg, 1964, 89: 244- 249.
[30] Edeline J, Gilabert M, Garin E, et al. Yttrium- 90 microsphere radioembolization for hepatocellular carcinoma[J]. Liver Cancer, 2015, 4: 16- 25.
[31] Ehrhardt GJ, Day DE. Therapeutic use of 90Y microspheres[J]. Int J Rad Appl Instrum B, 1987, 14: 233- 242.
[32] 黄文旵, 钱达兴, 周 萘, 等. 辐射治疗玻璃微球的制备与应用[J]. 玻璃与搪瓷, 2002, 30: 13- 16.
[33] 周 萘, 钱大兴, 黄文旵. 用溶胶-凝胶法制备医疗微球的若干工艺因素[J]. 玻璃与搪瓷, 1997, 25: 1- 5.
[34] Schubiger PA, Beer HF, Geiger L, et al. 90Y- resin particles: animal experiments on pigs with regard to the introduction of superselective embolization therapy[J]. Int J Rad Appl Instrum B, 1991, 18: 305- 311.
[35] Grady ED. Internal radiation therapy of hepatic cancer[J]. Dis Colon Rectum, 1979, 22: 371- 375.
[36] Mantravadi RV, Spigos DG, Tan WS, et al. Intraarterial yttrium - 90 in the treatment of hepatic malignancy[J]. Radiology, 1982, 142: 783- 786.
[37] 刘学成. 国外安全运输放射性物质的管理与防护简介[J]. 铁道劳动安全卫生与环保, 1985, 11: 59- 63.
[38] Salem R, Thurston KG. Radioembolization with 90Yttrium microspheres: a state- of- the- art brachytherapy treatment for primary and secondary liver malignancies. Part 1: Technical and methodologic considerations[J]. J Vasc Interv Radiol, 2006, 17: 1251- 1278.

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备注/Memo

备注/Memo:
(收稿日期:2017-02-16)
(本文编辑:俞瑞纲)
更新日期/Last Update: 2017-10-15